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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).
Scopus Indexed (link http://www.scimagojr.com/journalsearch.php?q=21100325431&tip=sid&clean=0) 

Journal Metrics for this Journal of Pharmacy Research (Source ID: 21100325431): 2015(SNIP) Source Normalized Impact Per Paper : 0.575; SCImago Journal Rank (SJR):0.787; Impact Per Publication : 0.789 CiteScore 2016: 0.93(Top level : Life Science)

Year SJR Cites per document Year Value
2014 0.607 Cites / Doc. (4 years) 2014 0.607
2015 0.787 Cites / Doc. (4 years) 2015 0.789
2016 0.926 Cites / Doc. (4 years) 2016 0.926
    Cites / Doc. (3 years) 2014 0.607
    Cites / Doc. (3 years) 2015 0.789
    Cites / Doc. (2 years) 2014 0.607
    Cites / Doc. (2 years) 2015 0.789
2016   Cites / Doc. (4 years) 2016 0.926
Cites Year Value
External Cites per document 2014 0.607
External Cites per document 2015 0.789
External Cites per document 2016 0.926
Cites per document 2014 0.607
Cites per document 2015 0.789
Cites per document 2016 0.926

Manuscripts Published

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-PA-0000692
Title: Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
Category: Pharmaceutical Analysis
Section: Research Article
Country: India
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A simple, sensitive, reproducible and cost effective stability indicating UV Spectrophotometric method has been developed for quantitative determination of Sitagliptin Phosphate in bulk and pharmaceutical formulations. The UV spectrum was scanned between 200 to 400 nm and 267 nm was selected as maximum wavelength for absorption. Beer’s law was obeyed in the concentration range of 10-100 mg/ml. Good accuracy (99.87-100.45%), precision (%RSD 1.3147-1.2957) were found, the method was successfully applied to the pharmaceutical dosage form containing the above-mentioned drug without any interference by the excipients. The limit of detection and limit of quantification was found to be 0.16 ìg/ml & 0.45 ìg/ml respectively. Results of the analysis were validated as per ICH guidelines. Forced degradation studies includes the effect of temperature, oxidation, photolysis and susceptibility to hydrolysis across a wide range of pH values, were carried out according to the ICH requirements which can be used for the routine and quality control analysis of Sitagliptin Phosphate in raw material and pharmaceutical formulations.

Cite this article as: Parag Pathade , Md Imran ,Vinod Bairagi , Yogesh Ahire,Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form,Journal of Pharmacy Research 2011,4(3),871-873.

 

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-PCS-00001344
Title: Analytical method development and validation of aliskiren in bulk and tablet dosage form by RP- HPLC method
Category: Pharmaceutics
Section: Research Article
Country: India
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A simple, accurate, precise, and reproducible reverse phase liquid chromatographic method developed and validated for the quantification of Aliskiren in bulk drug and in Pharmaceutical dosage form. Separation was achieved under optimized chromatographic condition on a PhenomenaxLunaC18 (ODS) column (150 X 4.6 mm i.d., particle size 5m). The mobile phase consisting of phosphate buffer pH 3.0: Acetonitrile (60:40, v/v). An isocratic elution was achieved at a flow rate of 1 ml/ min at ambient temperature. The detection was carried out at 293nm using Shimadzu UV-Visible detector SpD-10AVP. The retention time of Aliskiren was found to be 5.02 min. The calibration curve was linear in the concentration range of 5-30mg/ ml (r2- 0.9999).The limit of detection and the limit of quantification were found to be 0.580531 mg/ml and 1.75918mg/ml respectively. The amount of Aliskiren present in the formulation (Tekturna) was found to be 99.79 ± 0.8075. The method was validated statistically using the SD, %RSD and SE and the values were found to be within the limits. The recovery studies were performed and the percentage recoveries were found to be 101.10±1.635%. So, the proposed method was found to be simple, specific, linear, and rugged. Hence it can be applied for routine analysis of Aliskiren in bulk and pharmaceutical formulation.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-PC-00001351
Title: Recent advances in pharmacological activities of quinoxaline derivatives
Category: Pharmaceutical Chemistry
Section: Review Article
Country: India
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Quinoxalines are well known and important nitrogen-containing heterocyclic compounds containing a ring complex made up of a benzene ring and a pyrazine ring. Diversely substituted quinoxalines and their derivatives embedded with variety of functional groups are important biological agents and a significant amount of research activity has been directed towards this class. Various methods have been worked out for their synthesis. Numerous quinoxaline derivatives have been found to possess considerable biological activities, which stimulated the research activity in this field. They have several prominent pharmacological effects, such as antimicrobial, antimycobacterial, antifungal, antiviral, antiprotozoal, antimalarial, antiinflammatory,anticonvulsant, antidepressant and anticancer activities. They also possess some potent receptor selective biological activity like AMPA receptor antagonist activity. Quinoxaline 1,4-di-N-oxides seem to be the most frequently studied quinoxaline type compounds. As a result, a large number of such quinoxalines using different synthetic methods for their preparation have been described in the chemistry literature. The present review provides an insight view to quinoxaline synthesis and its biological activities along with the compilation of recent patents on quinoxaline.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-PC-00001352
Title: Chromolaena odorata (L.) : An Overview
Category: Pharmaceutical Chemistry
Section: Review Article
Country: India
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Chromolaena odorata is a species of flowering shrub in the sunflower family, Asteraceae.It is native to North America, from Florida and Texasto Mexico and the Caribbean, and has been introduced to tropical Asia, west Africa, and parts of Australia. It is used as atraditional medicine in Indonesia. The young leaves are crushed, and the resulting liquid can be used to treat skin wounds. According to traditional healing in yucatan, the boiled roots of Chromolaena odorata are used for urinary retention and leaves are used to cure malaria, gonorrhea, ulcers and blood in urine. The kani tribals of Kouthalai in Tirunelvelli hills used the leaves extract to cure skin diseases, poison bites, wounds and rheumatism. Following various folk claims for the ailment of various diseases, efforts have been made by the researchers to verify the efficacy of this weed through scientific biological screenings. A scrutiny of the literature revealed some notable pharmacological activities of the shrub like anthelmintic, Antimalerial, analgesic, anti-inflammatory, antipyretic, antispasmodic, antioxidant, antigonorrheal, antimycobacterial, insecticidal, fungicidal, wound healing, diuretic, blood coagulation, antibacterial. The present review is an attempt to highlight the various ethnobotanical and traditional uses as well as the phytochemical and pharmacological reports on Chromolaena odorata L.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-PB-00001359
Title: A Review: Bacterial Endophytes and their Bioprospecting
Category: Pharmaceutical Biotechnology
Section: Review Article
Country: India
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Endophytic bacteria have been found in almost every plant studied practically. They inhabit the internal tissues host plants. Endophytes can also be beneficial to their host plant by producing a range of natural products that could be use in medicine, agriculture and industry. This review describes information on the role of endophytic bacteria and some of naturally occurring bioactive compounds obtained from endophytes isolated from a variety of host plants. A great deal of information on the role of these microbes in nature has been collected up to date. The main topics addressed are bacterial endophyte, host endophyte relationship, their diversity, role of endophyte in environment, phytoremediation, biological activities, genomics, and natural products derived from endophytic bacteria.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-PCS-00001369
Title: Niosomes: A Review
Category: Pharmaceutics
Section: Review Article
Country: India
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Niosomes or non-ionic surfactant vesicles are microscopic lamellar structures formed on admixture of non-ionic surfactant of the alkyl or dialkyl polyglycerol ether class and cholesterol with subsequent hydration in aqueous media. They are vesicular systems similar to liposomes that can be used as carriers of amphiphilic and lipophilic drugs. The method of preparation of niosome is based on liposome technology. The basic process of preparation is the same i.e. hydration by aqueous phase of the lipid phase which may be either a pure surfactant or a mixture of surfactant with cholesterol. After preparing niosomal dispersion, unentrapped drug is separated by dialysis centrifugation or gel filtration. A method of in-vitro release rate study includes the use of dialysis tubing. Niosomes are promising vehicle for drug delivery and being non-ionic, it is less toxic and improves the therapeutic index of drug by restricting its action to target cells. Niosomes are unilamellar or multilamellar vesicles formed from synthetic non-ionic surfactants. They are very similar to the liposomes. Niosomal drug delivery is potentially applicable to many pharmacological agents for their action against various diseases. Niosomes have shown promise in the release studies and serve as a better option for drug delivery system.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: 3.
Article Id: JPRS-ND-00001376
Title: GC-MS study and phytochemical profiling of Mimosa pudica Linn.
Category: Natural Drugs
Section: Research Article
Country: India
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Several studies have proved that the phytocomponents present in a medicinal plant are widely responsible for the therapeutic potential of the plant. In the present study, Gas chromatography – Mass Spectrum (GC – MS) was carried out on the methanol extract of a medicinal plant Mimosa pudica Linn for identification of phytocompounds in the plant. The results showed the presence of a number of bioactive phytocompounds like glycerin, phytol, myo-inositol and squalene all of which possessed a wide range of proven therapeutic uses.