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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).
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Journal Metrics for this Journal of Pharmacy Research (Source ID: 21100325431): 2015(SNIP) Source Normalized Impact Per Paper : 0.575; SCImago Journal Rank (SJR):0.787; Impact Per Publication : 0.789 CiteScore 2016: 0.93(Top level : Life Science)

Year SJR Cites per document Year Value
2014 0.607 Cites / Doc. (4 years) 2014 0.607
2015 0.787 Cites / Doc. (4 years) 2015 0.789
2016 0.926 Cites / Doc. (4 years) 2016 0.926
    Cites / Doc. (3 years) 2014 0.607
    Cites / Doc. (3 years) 2015 0.789
    Cites / Doc. (2 years) 2014 0.607
    Cites / Doc. (2 years) 2015 0.789
2016   Cites / Doc. (4 years) 2016 0.926
Cites Year Value
External Cites per document 2014 0.607
External Cites per document 2015 0.789
External Cites per document 2016 0.926
Cites per document 2014 0.607
Cites per document 2015 0.789
Cites per document 2016 0.926

Manuscripts Published

Journal: Journal of Pharmacy Research , Volume: 6, Issue: 8.
Article Id: JPRS-BMB-00001305
Title: A detail study of phytochemical screening, antioxidant potential and acute toxicity of Agaricus bisporus extract and its chitosan loaded nanoparticles
Category: Biochemistry and Molecular Biology
Section: Research Article
Country: India
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Aim: Scrutinize the phytochemical, antioxidant and acute toxicity of Agaricus bisporus extract (ABE) and A. bisporus loaded chitosan nanoparticles (ABCNPs). Methods: Phytochemical such as total phenol and flavonoid, and terpenoid, alkaloid, steroid, carbohydrate, tannins and proteins where determined. The antioxidant activity such as DPPH, ABTS and reducing power of ABE and ABCNPs where estimated by spectrophotometry assay. The estimation of total phenolic content was determined by Foline Ciocalteu method. The acute toxicity studies of ABE and ABCNPs were investigated in male Sprague Dawley rats. Results: In the DPPH, ABTSþ and reducing power scavenging assays, of ABE displayed significant antioxidant activities with the inhibition values of 27.78, 27.62 and 81.97% and ABCNPs inhibition values 27.78, 27.62 and 78.13% respectively. The reducing power of the extract increased dose-dependently, and the ABE and ABCNPs reduced the most Fe3þ ions. The amount of total phenolics was reported 1 g of sample contains 8.191 mg of gallic acid and total flavonoid analysis by the assay of aluminum chloride spectrophotometric reported 1 g of sample contains 10.3  1 mg of quercetin in ABE and ABCNPs. The acute toxicity was found bellow 2747.25 mg/kg b.w. in ABE and 3178.86 mg/kg b.w. of ABCNPs. Conclusion: The white button mushroom A. bisporus could be considered as a dietary natural food products with antioxidant activity. Thus our results provide evidence that AB and ABCNPs proves to have a potent antioxidant and intermittent therapy against cancer.

Journal: Journal of Pharmacy Research , Volume: 6, Issue: 8.
Article Id: JPRS-P'Col-00001306
Title: Liver protective effects of aqueous extract of Syzygium cumini in Swiss albino mice on alloxan induced diabetes mellitus
Category: Pharmacology
Section: Research Article
Country: India
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Background: Diabetes mellitus is one of the most common endocrine disorders accompanied with many metabolic syndromes. Use of herbal medicines has always been an option to treat a great number of diseases such as diabetes and its complications. The aim of the present study is to investigate the liver protective effects of Syzygium cumini seed extract in alloxan induced diabetic Swiss albino mice. Methods: Eighteen Swiss albino mice (weighing 28e32 g) were randomly divided into control, alloxan treated and S. cumini treated mice group. Diabetes was induced in mice by injecting intraperitoneally alloxan monohydrate at dose of 150 mg/kg body weight. Aqueous extracts of S. cumini seed at dose of 250 mg/kg body weight were given orally in diabetic mice daily for three weeks after established LD50 value. Results: In diabetic mice, the SGOT, SGPT, Bilirubin and serum glucose levels were significantly increased in comparison with the control groups. Statistical analysis ( p < 0.05) of the data indicated that aqueous extract of S. cumini were significantly decrease serumcontents of liver enzymes (SGOT, SGPT and Bilirubin) as well as serum glucose in treated groups. Conclusion: The results suggested that aqueous extracts of S. cumini seed possesses liver protective effect against alloxan induced diabetic mice.

Journal: Journal of Pharmacy Research , Volume: 6, Issue: 8.
Article Id: JPRS-P'Col-00001307
Title: Pilot study: Hypoglycemic and antiglycation activities of bitter melon (Momordica charantia L.) in type 2 diabetic patients
Category: Pharmacology
Section: Editorial
Country: India
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Background/Objectives: Bitter melon (Momordica charantia L., MC) has been used as a traditional remedy in diabetics due to its hypoglycemic activity. However, its antihyperglycemic effect and antiglycation activity have been demonstrated in vitro and in animal experiments, but not in a long-term clinical study. The aim of this study was to investigate the effect of bitter melon on long-term glycemic control and glycation status in type 2 diabetic patients. Methods: This study was a two-arm, parallel, randomized, double-blinded, placebocontrolled trial in which type 2 diabetic patients were randomized to continuously take either 6 g/day of MC dried-fruit pulp containing 6.26  0.28 mg of charantin (N = 19) or placebo (N = 19) for 16 weeks. Results: After 8 and 16 weeks of the treatment, the reduction of A1C frombaseline in the MC group was greater than that of the placebo group (0.25  0.12%, P = 0.042 and 0.31  0.15%, P = 0.044, respectively). In addition, the MC group showed a significant decline of total advanced glycation endproducts (AGEs) in serum after 16 weeks of the intervention. The mean difference between both groups was 8.22  3.58  103 AU/g protein (P = 0.028). The levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and serum creatinine (Cr) did not change from baseline in each group and were not different between the two groups. None of participants experienced serious adverse events. Conclusions: It is possible that this herb is beneficial not only on glycemic control, but also on potential systemic complications of type 2 diabetes mellitus.