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Drug Invention Today
ISSN NO: 0975-7619
Drug Invention Today (DIT) was first published in 2009 by JPR Solutions. It is a journal, which publishes reviews, research papers and short communications . From 2019  Journal will be monthly twice ( vol 11& 12 with 2 Issues per month)
• Novel Drug Delivery Systems • Nanotechnology & Nanomedicine • Biotechnology related pharmaceutical technology • Polymeric bio-conjugates • Biological macromolecules • Biomaterials • Drug Information • Drug discovery/development • Screening of drugs from natural & synthetic origins • Novel therapeutic strategies • Combinatorial chemistry and parallel synthesis • Clinical trials • Case Reports
 Impact FactorTM ( India ) = 0.895 as on date (09.11.2018)
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Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004882
Title: A review of chemical tools for induction of cardiotoxicity
Category: Pharmacology
Section: Review Article
Author Affiliation: Department of Pharmacology, Krupanidhi College of Pharmacy, Bangalore, Karnataka, India
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Congestive heart failure involves considerable damage to the heart tissue caused by severe chlorosis and oxygen deprivation. This arises most frequently during the degradation of the atherosclerotic plaque and leads to the development of pulmonary embolism in the coronary artery. Structural changes include the development of anastomotic channels, dilation of artery, formation of atherosclerotic plague, and insufficient blood circulation to the cardiac tissue through coronary blockade. There are several models of the induction of myocardial infarction (MI) such as coronary artery ligation, closed-chest form, coronary artery embolization, ameroid constrictor, and cryoinjury. As these procedures have many drawbacks such as complex treatment, anesthetic risks, lengthy recovery periods, poor success rate, high death rates, systemic, and local immunological and inflammatory reactions and require advanced technical expertise, hence induction by chemicals can be used as alternative method against the surgical procedures due to their high success rate, simple technique, fast and less complicated non- invasive method, and no technical skills required. This latest review aims to explore the chemicals used for the induction of MI such as isoproterenol, 5-fluorouracil, doxorubicin, and cisplatin, in which their detailed mechanisms, dose of inductions, and their supported literature such approaches may be of interest to scholars and investigators interested MI with therapy.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004883
Title: Community Pharmacist and General Practitioner Collaborated Health Care Services - A Review
Category: Pharmacology
Section: Review Article
Author Affiliation: Department of Paediatric, JSS Medical College and Hospital (Affiliated to JSS Academy of Higher Education and Research), Mysore, Karnataka, India
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Home medicines review (HMR) services were specifically created to assist elderly patients residing in their homes to have more benefits of medication regimen that can help them in understanding the importance of medications through medication review by community pharmacist and HMR services were rendered with the intention of minimizing medication-related problems. The successful operation of HMR depends on good coordination between patients, general practitioner (GP), and accredited pharmacist. In some circumstances, other health-care team members such as nurses in community practice can also play an important role in ensuring whether patient is following correct administration guidelines of medicine or not. The common screening of medications carried out by community pharmacist was reflected with checking rationality of drug, over the counter medicinal products, patient medication adherence, drug therapy monitoring whether signs and symptoms are minimized or subsided. If drug-related problems were identified they were communicated to concerned patient consultant through HMR report and requested to make certain changes in drug therapy management in according to severity of drug- related problem.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004884
Title: Methods of induction of Alzheimer’s disease in rat and mice
Category: Pharmacology
Section: Review Article
Author Affiliation: Department of Pharmaceutical Chemistry and Analysis, Faculty of Pharmacy, Dr. M.G.R Educational and Research Institute, Velappanchavadi, Chennai, Tamil Nadu, India.
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Alzheimer’s disease is known to be progressive dysfunction of neurons, which could be categorized under hereditary and sporadic conditions. The common cause of 70% of dementia, progression initiates slowly and thus worsens over a gradual increase of time. Noticed at an older age, especially geriatric level, which is difficult to attain relevant results in treatment. The cause of AD is undisclosed. The trademark of Alzheimer’s disease is found to be deposition of peptides of β-amyloid, resembling a plague appearance in the central nervous system. The plague formed is expected to increase in size at the later stage. Initially, the disease is encountered with loss of memory, inability to recollect the recent issues practiced by the patient, especially of episodic memory. Different methods had been carried for induction of AD in mice through animal modeling technique, subsequent treatment to solubilize the plague is attained. The underlying mechanism of the disease progression could be explained through genetically modified animals which would support to attain therapeutic interventions and preclinical drug development. Combined deposition of Cu and Zn in Aβ is enriched and thus solubilized by Cu/Zn chelators in vitro, which would serve as a novel therapy for the prevention and treatment of AD. A comprehensive literature search has been carried out in PubMed and Google Scholar, and articles pertaining to complications of intravenous drug use were selected for review.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004885
Title: An updated review on various pharmacological activities of Phaseolus vulgaris Linn.
Category: Pharmacology
Section: Review Article
Author Affiliation: Department of Pharmacology, Krupanidhi College of Pharmacy, Bengaluru, Karnataka, India
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Phaseolus vulgaris that belongs to the Leguminosae family is one of the most commonly used as a food source, with a wide range of medicinal properties. In this paper, we review the latest research works which describe the origin, taxonomical classification, and pharmacological activities to help researchers to carry out further research to find out novel phytochemicals. Articles have been obtained from databases such as PubMed and Google search engines by entering some related terms such as P. vulgaris, traditional use, and pharmacological properties. The literature survey yielded 12 articles and among them, 2 articles were excluded as they are irrelevant to the subject. From the articles we reviewed, it is found that P. vulgaris possessed various pharmacological activities (e.g., angiotensin-converting enzyme inhibitor property, antihyperglycemic, antihyperlipidemic, antihypertensive, anti-inflammatory, anti-obesity, etc.). This review paper provides worthy scientific data for further research on P. vulgaris plants that might be utilized for the isolation of powerful active molecules in future.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004886
Title: Evaluation of antifungal potential of fruiting body extracts of Pleurotus ostreatus in vitro and in vivo study
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Basic Science, College of Dentistry, Wasit University, Kut, Iraq.
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Background: The recent development of fungal resistant strains has raised worry in health care settings in Iraq. This has led to increased research interest in mushrooms. The current research explores the medical possibility of the cultivated mushroom Pleurotus ostreatus as a hopeful antifungal agent against divers’ clinical fungal pathogens that are resistance to present generation antifungals. Materials and Methods: Samples are going to be registered during this study is mushroom belong the genus P. ostreatus was obtained from Unit of Fungal Production/Unit of Medicinal and Aromatic Plants/College of Agriculture/University of Baghdad Code No. MF0657151 that is recorded in the National Center for Biotechnology Information/Part of (US National Institute of Health). Candida albicans was already isolated and diagnosed from the previous study and preserved in the lab. The general technique of extraction from the powder of P. ostreatus fruiting bodies was done by three solvents consecutive (chloroform, methanol, and aqueous) solutions. The antifungal activity was assessed using agar well diffusion procedure; 200 mg/ml from every crude extract are used. The antifungal activity and minimum inhibitory concentration (MIC) were assessed for methanol crude extract for (the potent solution among the others) within the starting from 100, 50, 25, and 12.5 mg/ml. Murine model was wont to assess the antifungal activity of methanol crude extract after cutaneous induced infection of a clinical infection agent, C. albicans. Results: It was seen that the most effective extract was this belongs methanol. The foremost potent antifungal activity of methanol crude extract was seen within the range of 100 mg/ml–12.5 mg/ml concentrations. Methanol crude extract exhibited the most potent inhibitory effect against C. albicans growth with MIC 25 mg/ml. In the case of in vivo study and concerning C. albicans, it was absolutely found a significant difference (P < 0.05) using methanol crude extract. Conclusions: Methanol crude extract of P. ostreatus was the powerful one as antifungal agent against the tested C. albicans in vitro and in vivo study than the others.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004887
Title: Comparative study of intravitreal ranibizumab injection and intravitreal triamcinolone injection in diabetic macular edema
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Pharmacology, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai - 600 117, Tamil Nadu, India.
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Purpose: Diabetes is a leading cause of diabetic retinopathy. Diabetic macular edema (DME) or retinal thickening is an important manifestation of diabetic retinopathy. There is a necessity of treatment so as to reduce the risk of irreversible damage of macula and thereby permanent vision loss. In this study, reliable treatment for macular edema with maximum effectiveness and minimal side effects was assessed. This study compared the effectiveness of intravitreal ranibizumab (IVRB) injection and intravitreal triamcinolone (IVTA) injection in reducing the central foveal thickness (CFT) and in improving the visual acuity. Materials and Methods: This prospective study was conducted among 60 patients who were diagnosed with DME and randomly divided into two groups. The first group of 30 patients received IVRB at a dose of 0.5 mg/0.05 ml, whereas the second group, comprising 30 patients, received IVTA at a dose of 4 mg/0.1 ml. Visual acuity and CFT measures were assessed from logarithm of the minimum angle of resolution chart and optical coherence tomography, respectively. These parameters noted at baseline, 3 months, and 6 months interval. The safety and efficacy of IVRB were compared with IVTA and analyzed statistically by statistical software SPSS with 95% confidence interval. The safety of the drug was assessed by side effects measurement. Results: After 6 months, the statistical comparison was done for ranibizumab and triamcinolone administered groups. Ranibizumab was found to be significantly more effective (P < 0.05) than triamcinolone in case of improving visual acuity as there was an improvement in visual acuity from 0.77 ± 0.15 to 0.36 ± 0.19, whereas in triamcinolone group, the visual acuity does not show much improvement as the resulted values were 0.76 ± 0.15–0.60 ± 0.15, after 6-month follow-up. In case of reduction in CFT, ranibizumab was 371.6 ± 42.8 and triamcinolone was 369.2 ± 42.8 at baseline and significantly reduced to 250 ± 41.2 and 247.8 ± 43.3 at the end of 6-month follow-up, respectively, which showed less significant difference between IVRB and IVTA but significantly effective when compared to uninjected eye. Side effects such as increased intraocular pressure and eye infection were noted. Conclusion: In contrast to intravitreal triamcinolone, IVRB resulted in statistically significant improvement and reduced side effects. Hence, IVRB injection was found to be safe and effective treatment for DME.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'ceu-00004888
Title: Adaptations of Pharma 4.0 from Industry 4.0
Category: Pharmaceutics
Section: Review Article
Author Affiliation: Department of Pharmaceutics (Pharmaceutical Quality Assurance), JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India
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Pharma 4.0 conceptualizes extremely systematic automated processes, which could be batch, continuous, or a hybrid of these, operated by an integrated manufacturing control strategy. Quality by design and process analytical technology principles are used to strengthen the hypothesis of Pharma 4.0. These provide the potential for robust, efficient, and quickproduction. Industry 4.0 is employed in medical technology, health-care facilities, and biopharmaceutical manufacturing. Digital transformation plays a major role. Pharma 4.0 provides better instruments to enforce product safety and supply chain security. This review explains the impact of data analytics technology, digitization, industry 4.0, artificial intelligence, digital twins, and continuous manufacturing and their impact on Pharma 4.0.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004893
Title: Prevalence and awareness on computer vision syndrome among individuals in information technology
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of General Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: Computer vision syndrome (CVS)/digital eye strain is a condition in which a person experiences one or more of eye symptoms as a result of prolonged working on a computer. Although the world’s advanced technology is causing new syndromes and diseases, CVS has been affecting individuals for quite some time. Materials and Methods: CVS affects people of all age groups. It leads to a various bunch of problems. A cross-sectional survey was conducted among 100 people. People were asked if they were aware or unaware of the CVS and its symptoms also choices were asked for the preferred eye protectives used. Results and Discussion: The results proved that the awareness of the symptoms of CVS among the study population, which shows about 70% of the population is unaware of it. About 42% of the study population views the display at about 4–5 inches below the eye level. The majority of the population were aware of preventive measures. Conclusion: The current study evidently proved that there are a lot of people in the present population who are unaware of the symptoms of CVS.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004894
Title: Isolation, identification, and genetic study for bacterial infection from non-lactating women with acute mastitis
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Pathology, Faculty of Medicine, College of Medicine, University of Wasit, Iraq.
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Background: Mastitis is an inflammation of the breast, which may or may not relate with bacterial infection. The aim of this study isolates the most prevalent causative of bacteria in acute mastitis in non-lactating women and molecular study for more predominant bacterial isolate from nipple discharge using polymerase chain reaction (PCR). Methodology: Then we used both aerobic and an aerobic environmental condition for growth of bacterial culture (blood agar, macConkey agar, chocolate agar and mannitol salt agar), biochemical test, sensitivity test, API, Vitek, additionally using 16SrRNA gene for more accurate identified isolates, also using PCR for detection of some virulence gene and phylogenic analysis to confirms diagnostic of bacteria. We were collect 56 swab nipple discharge samples from breast of non-lactating women that suffer from acute mastitis and studied in laboratory for diagnosis. Results: The results revealed that the highest bacteria that cause acute mastitis in non-lactating women were Staphylococcus epidermidis and the results are as follows: S. epidermidis (78.43%), Pseudomonas stutzeri (5.88%), Pseudomonas oryzihabitans (5.88%), Pseudomonas aeruginosa (1.96%), Klebsiella pneumoniae (1.96%), Streptococcus viridans (3.92%), and Acinetobacter baumannii (1.96%). The results of antibiotic sensitivity for S. epidermidis were sensitive to imipenem, gentamycin, amikacin, ciprofloxacin, piperacillin, azithromycin, and clindamycin, respectively. P. aeruginosa showed sensitivity to imipenem, amikacin, ciprofloxacin, and ceftriaxone, respectively.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-PS-00004896
Title: Comparison of effects of interpretation of lab reports among the undergraduate dental students
Category: Pharmacological Screening
Section: Research Article
Author Affiliation: Department of Pathology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: The enthusiasm in clinical pathology is piqued, as we recognize the captivating power of laboratory data to expose and make clear the concealed disease. Diagnosis of the various hematological disorders is made possible by interpreting a lab report with the aid of comparing the known standard normal values with the obtained lab report value. This study was done to analyze whether the students have intact knowledge on interpretation of the lab reports even after passing out of their 2nd year. Materials and Methods: The study population comprised a total of 50 members. Data-1 were collected from the marks of model practical exam obtained by the study population in their 2nd year of college of dentistry. Data-2 were collected from the marks obtained by the study population in the exam which was conducted without any prior knowledge or revision. The data 1 and data 2 were compared and statistically analyzed using paired t-test. Results: There is a gradual decrease in average value among the study population after passing out of 2nd year, which indicates that there is a slight deterioration in the knowledge of interpreting a lab report. Conclusion: There is a significant difference between the knowledge of interpreting a lab report in the student population after passing out of 2nd year.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004897
Title: Antihyperlipidemic effect of Kaempferia galanga in streptozotocin-induced diabetic rats
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Biochemistry, Dr.N.G.P. Arts and Science College, Coimbatore - 641 014, Tamil Nadu, India
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Background: Diabetes mellitus is one of the worldwide increasing problems characterized by metabolic deregulation. One of the major factors contributing to cardiovascular risk in patients with Type 2 diabetes is abnormalities of lipoprotein metabolism. Due to various side effects caused by available drugs, the search for new antidiabetic and antihyperlipidemic drugs from herbal plants has become essential. Aim: The present study was carried out to evaluate the antihyperlipidemic potential of hydroethanolic extract of Kaempferia galanga rhizome in streptozotocin (STZ)-induced diabetic rats. Materials and Methods: Male albino Wistar rats (6 weeks old), weighing 170–200 g, were used for the present study. Diabetes was induced by intraperitoneal injection of STZ at a dose of 60 mg/kg body weight (bw). Oral administration of hydroethanolic extract of K. galanga rhizome at 250 mg/kg bw and 500 mg/kg bw was carried out for 28 days. Blood was collected by cardiac puncture and the serum was separated and analyzed for biochemical parameters. Results: The reports showed a significant reduction in the levels of protein, total cholesterol, phospholipids, triglyceride, very low-density lipoproteins (LDL), and LDL compared to the diabetic group which was reverted to near-normal levels in treated groups. The level of high-density lipoprotein cholesterol significantly increased in treated groups with the improvement of diabetic dyslipidemia. Conclusion: The present findings infer that the rhizome extract is capable of controlling hyperlipidemia. Further studies can be carried out to isolate the active compound for the management of diabetes-induced complications.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'ceu-00004898
Title: A perspective view on nanosponge drug delivery system
Category: Pharmaceutics
Section: Review Article
Author Affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute (Deemed to be University), Velappanchavadi, Chennai - 600 076, Tamil Nadu, India.
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Targeting drug delivery has long been a problem for medical researchers to get them to their right place in the body and how to control the release of the drug to prevent overdose. The development of new and complex molecules called nanosponges has the potential to solve these problems. Nanosponge is a novel and emerging technology which play a key role in targeting drug delivery in a controlled manner. It is a new class of materials and made of microscopic particles with few nanometers wide cavities in which a large variety of substances can be encapsulated. To overcome the problems of bioavailability, of which nanosponge is an advanced drug delivery system which offers diverse advantages than the other available systems. Nanosponge is based on nano, polymer-based spheres that can suspend or entrap a wide variety of substances and then be incorporated into a formulated product such as a gel, lotions, cream, ointments, liquid, or powder. This technology offers entrapment of ingredients and thus reduced side effects, improved stability, increases elegance, and enhanced formulation flexibility. This review article deals with the general introduction of nanosponges, characteristic features of nanosponges, their advantages, disadvantages, preparation methodologies, factors affecting on their preparation, and with some referential examples of nanosponge drugs.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004899
Title: Awareness of the side effects of vaccination among general public
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of General Pathology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Aim: This study aims to evaluate and create awareness of the general public on the side effects of vaccination. Objective: The objective of the study was to assess the awareness levels of general public on importance and side effects of vaccination to improve the standard of health care. Materials and Methods: The present study was conducted in Chennai among randomly selected people using a questionnaire. The question was related to knowledge and awareness of vaccination and its side effects. A total of 20 close-ended questions were included in the study. The results were being analyzed using statistical software. Results: The obtained results shows that 55% are aware of the benefits of vacciation and 85% of respondants have experienced the side effects like pain, fever, swelling, redness and headaches. Conclusion: On analyzing the results obtained from the present study, it is clear that people are fairly aware and has a knowledge about vaccination and about its benefits as well as side effects.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004900
Title: Evidence-based clinical practice guidelines for topical fluoride application
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Public Heath Dentistry, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth, Pondicherry, India
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Introduction: Dental caries is a global oral health problem which has a distinctive variation. Prevention of dental caries in children and adolescents is generally regarded as a priority for dental services and considered more cost-effective than its treatment. Fluoride is the primary agent available for caries prevention. It can be taken both systemically and topically. The aim of this report is to update the evidence at the 5-year interval according to American Dental Association (ADA) policy and address additional questions related to the use of prescription-strength, home-use topical fluorides. Materials and Methods: A systematic search was conducted in databases such as PubMed, Cochrane, and Google Scholar. A group of six examiners was involved in the process identifying the clinical problems which were then converted to research questions for which the committee aimed at providing evidence-based recommendations. The same set of examiners was involved in the selection of articles and all the examiners graded each article based on the evidence. Results: The systematic search revealed a total of 27 publications from PubMed and Google Scholar which were scrutinized based on pre-set inclusion and exclusion criteria. Fluoride induced faster remineralization than other remineralizing agents. Appropriate use of fluorides may help in the prevention of dental caries. Conclusion: With the evidence available, it can be concluded that all age and risk groups must use an appropriate amount of fluoride toothpaste when brushing twice a day. Fluorides irrespective of forms and methods of application are effective in preventing dental caries.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004901
Title: A comparative study of prostaglandin analogs and ocular beta-blockers on intraocular pressure reduction
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Pharmacology, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, Tamil Nadu, India.
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A comparative study on effectiveness of topical ocular medications, latanoprost and timolol, in intraocular pressure (IOP) reduction was done. IOP was obtained from primary open-angle glaucoma (POAG) and also from ocular hypertensive patients before commencement of therapy and after commencement of therapy on 2nd and 4th months. Other than IOP, central corneal thickness (CCT) parameter was also used. CCT is a predictive parameter in the development of glaucoma from ocular hypertension. There is a greater risk of developing POAG if CCT is 555 µm or less compared corneal thickness of more than 588 µm. The mean IOP before commencement of treatment was above 22 mm Hg in both the groups. By 2nd and 4th months after the commencement of therapy, mean IOP showed a significant improvement in both the groups especially in latanoprost administered compared to the timolol administered group. Increase in CCT by the 4th was also observed which is normal when IOP range becomes normalized. The study concluded that topical latanoprost 0.005% was more effective in reducing IOP than timolol maleate 0.5% twice daily.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004902
Title: Awareness and risk factors of atherosclerosis among working professionals – A survey
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: Coronary heart disease is a disorder of the heart usually caused by a condition called atherosclerosis. Atherosclerosis is one of the major and most frequent causes of heart arrest. Atherosclerosis is a group of disorders of heart and blood vessels in which the development of plaque occurs inside these arteries. Plaque is made of fatty substances, cholesterol, cellular waste products, calcium, and fibrin. Atherosclerotic plaque within the coronary arteries is responsible for coronary artery disease, myocardial infraction, and acute coronary syndromes. Atherosclerosis can lead to serious problems, including heart attack, stroke, or even death. Materials and Methods: This is a questionnaire-based survey which consists of 20 questions. A study was conducted among working professionals to assess the awareness and risk factors of atherosclerosis. The questionnaire was distributed through online survey planet link and it was circulated among 102 working professionals and the result was calculated statistically. Results: Hence, it is evident from the survey that the majority of the population are unaware of the risk factor such as cholesterol, obesity, high-density lipoprotein, and low-density lipoprotein (LDL) leads to atherosclerosis. Conclusion: From this survey, we can tell that 45% of the working professionals are only aware of the major risk factor LDL

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004903
Title: Preference of dental practitioners toward the use of polyalkenoate or resin cement for bonding all ceramic crowns
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: Dental crowns known as the tooth shaped restorations which can be positioned over tooth to cover it. It is used to restore the size, shape, strength, and improve its appearance. Ceramic crowns are helpful in restoring broken teeth, covering the a tooth with large filling when there is not a lot of tooth left, detaining a dental bridge, covering a dental implant, making cosmetic modification, and protecting a weak tooth from breaking or to hold together parts of a cracked tooth. Materials and Methods: A questionnaire was prepared and distributed to the dental faculty from which the preference level of polyalkenoate usage is estimated. The results are analyzed using statistical analysis. Results: According to the analysis taken among the current dental practitioner, it is clear they provide bonding of ceramic crown with the inorganic material such as polyalkenoate or resin. The awareness levels of dental practitioners are high and the standard of care provided for patients were monitored. Conclusion: Thus, from the above study, it is concluded that the preference toward the polyalkenoate or resin is high among current dental practitioners.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004904
Title: Awareness of root canal sealers among undergraduate dental students
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, No. 162 Poonamallee High Road, Velappanchavadi, Chennai - 600 077, Tam
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Introduction: Long-term success of a root canal treatment is based on the nature of the material used as a root canal sealer. The main components of a root canal filling are as follows: A solid core material and a sealer. The core material most commonly used is gutta-percha, which occupies the bulk of canal space, while the root canal sealer fills the space between the core material and the dentin wall, the voids inside the core material and the accessory canals and also serves as a lubricant, thus helping to obtain a fluid tight seal. Aim: The aim of this study is to evaluate the knowledge and awareness of dental students about the various root canal sealants available for use in dentistry. Materials and Methods: A questionnaire was distributed among 100 dental students to elicit the knowledge and awareness of root canal sealers. Data were gathered and analyzed using statistics and conclusions were drawn. Results: About 86% of the participants reported that they were actually aware of the various properties of root canal sealers. Considering calcium hydroxide-based sealers, 78% were aware, while 54% and 42% were aware of the various MTA-based sealers and bio-dentine, respectively. Conclusion: According to the findings of the present study, students had a higher level of knowledge about treatment and prognosis of procedural accidents than about the causes and prevention. This can be acquired due to clinical experience. The present study, considering the level of knowledge of dental students of Saveetha Dental College, can serve as a preliminary stage for future studies focusing on students’ performance.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004905
Title: Safety of female dentists working in private dental clinic, Chennai
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Background: Incidents of workplace violence are increasing worldwide. In general, the prevalence of violence on female is more compared to males. However, no studies have investigated this phenomenon from the perspective of female dentists working in private dental clinics. Aim: This study aims to assess the prevalence of violence and safety of female dentists working in private dental clinic, Chennai. Materials and Methods: An online questionnaire-based study was conducted among 96 female dentists working in private dental clinics in Chennai. A total of 10 questions consisting of both open-ended and closed-ended questions related to violence faced and safety measures incorporated were included in the questionnaire. Data were collected from the filled questionnaire and analyzed. Descriptive statistics were used. Results: Ninety-six female dentists participated in this study. It was reported that 78% have experienced workplace violence, of which 42% have faced violence at least once in their practice. About 87% felt that need of awareness programs on how to handle the situation and on the precautions to be taken for their safety in workplace environment is necessary. Conclusion: The prevalence of violence among female dentists working in private dental clinic is significantly high. They were given awareness and precautions on safety measures to be taken.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004906
Title: Sialography – A review
Category: Pharmacology
Section: Review Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.
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Sialography is the radiographic examination of salivary gland. Sialography involves injection of small amount of contrast medium into the ducted the salivary gland followed by routine X-ray projection. The first account of a sialogram carried out as a diagnostic measure appeared in 1925 when Barsony described a method of outlining the parotid duct, using 20% potassium iodide. This medium, however, proved to be so irritant that he abandoned the technique. A year later, the introduction of lipoid provided a further stimulus to this form of investigation, but, in spite of its widespread adoption, it was not until 1931 that R. T. Payne published the first of his classical series of papers on the subject. This review is done to analyze the role of sialography as a diagnostic aid.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004907
Title: Smoking habits among high school students
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: Cigarette smoking is a major preventable cause of morbidity and mortality worldwide. Most adult smokers start smoking regularly some time before 18 years of age. Aim: The aim of this study was to assess the reasons why children smoke. Materials and Methods: A cross-sectional survey of students aged between 11 and 17 years in two high schools in Chennai, using an anonymous self-completion questionnaire. The students were asked questions regarding the age at which they began smoking, initiation, their smoking habits, their reasons for smoking, and their views on children who smoke. In addition, they were asked about the smoking status of their parents, siblings, and friends. Finally, they were asked about the health hazards of smoking. Results: Of the 524 students who answered the questionnaire, 23% stated that they had smoked at least once and 14% stated that they were currently smoking. The most common reasons for starting to smoke were “to try something new” (55%), peer pressure 38%, and stress 13%. Conclusion: Smoking is moderately prevalent among schoolchildren in Chennai. The increase in the rate of smoking at the age of 12 years indicates that smoking prevention programs need to be started at an earlier age.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004908
Title: Standards of teeth preparation for anterior all-ceramic crowns in private dental practice
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Background: Tooth preparation is one of the important aspects of restorative dentistry because it establishes the foundation for whatever restoration is being placed. Understanding of tooth morphology is essential for developing preparations that will permit the restorations placed on them to be functionally durable, provide optimal esthetics, and be biologically compatible with the periodontal tissues. The most important aspect of tooth preparation is retention of the crown and esthetics, these two are governed by finish line. Hence, a proper, specific finish line has to be chosen for different types of crowns. Aim: This study aims to analyze the standards of teeth preparations for anterior all-ceramic crowns in private dental practice in India. Methodology: Hundred laboratory casts with tooth preparations for all-ceramic crowns for anterior teeth obtained from different general dental practitioners in Chennai were analyzed with inclusion criteria of fixed partial denture casts for anteriors for all-ceramic crowns and exclusion criteria of complete and removable partial denture dental casts. Result: The study revealed that 70% of the dentists preferred a supragingival margin for the tooth preparation. Almost 76% of the dentists made a reduction of 1–2 mm in the buccolingual and mesiodistal planes, whereas in terms of incisal reduction, 60% of the dentists reduced1–2 mm. Majority preferred radial shoulder finish line over other types, but a handful of them had no clear type of finish line being prepared with a depth in the range of 0.5 mm–1.5 mm and uniformity was being observed in 84% of the cases. An axial convergence of 6–10° was prepared by 56% of the dentists. Conclusion: This study showed that preparations for all-ceramic crowns of the Indian clinicians’ work investigated varied widely. Most of the clinicians follow proper tooth preparation principles while a handful of clinicians followed no specific principles. Hence, proper tooth preparation principles must be followed to ensure effective treatment in terms of esthetics and retention.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004909
Title: Student perception on the use of conceptual mapping as a learning method
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: The term concept mapping is typically associated with techniques used to identify relationships between ideas and the concepts. Students are encouraged to adopt this technique as a useful way to learn heavy course content. Concept mapping advocates the use of specialized analysis to investigate patterns in qualitative data. Aim: The aim of this study was to evaluate the perception of the student on conceptual mapping for learning. Materials and Methods: A questionnaire was be prepared and distributed to dental students in Saveetha Dental College. The questionnaire contains data about the convenience of using mind maps and software used for making mind maps. This survey was conducted among the students of Saveetha Dental College and about 100 participants were included in the study. The resulting data are analyzed using statistical software. The questionnaire includes the data of the participants such as their course of study, understanding and retention of their dental subjects, and awareness of the software used in making concept maps. Results: The data collected found that among 100 participants, 49 were 1st year students, 17 were 2nd years, 25 were 3rd years, and 9 were 4th years. Among these participants, they feel that dental subjects are slightly easy and difficult for more of them and they think that alternative methods are helping them out to study easily, wherein which 85% of the participants feel that conceptual mapping learning method helps them to understand their subject. Conclusion: Concept maps are very much helpful for dental students to learn and analyze their dental subjects and to improve their creativity.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004910
Title: Students perception on the use of video tutorials for learning preclinical prosthodontics
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Aim: The aim of this study was to evaluate the student perception on the use of video tutorials for learning preclinical prosthodontics. Methods: A questionnaire will be prepared and distributed to the dental students of the Saveetha Dental College. The resulting data will be analyzed using statistical software. The presence of our researchers in this present study, with different teaching experience and type of expertise, helped in better understanding of the research related issues from varying perspectives, thus helping in increasing the validity of the study. The study subjects knew the main investigator. Informed consent was taken from the participants. Results: In the survey conducted among 100 individuals of Saveetha Dental College, it is conducted among the individuals of the age range of 17–30 years. It had been observed that 85% of people feel comfortable to learn through video tutorials or preclinical experiences. About 84% of students are able to answer the question after watching the preclinical videos. About 75% of students feel that it is useful to learn through video tutorials for preclinical prosthodontics. Conclusion: The research had proved that difficulties going through by the professor and the pupil in teaching and learning of preclinical prosthodontics and it also includes their necessities for their improvement.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004911
Title: Study of digital denture systems among dental students
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.
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Introduction: Digital denture is the word used to describe the entire workflow involved in the fabrication of a computer-aided design and computer-aided manufacturing (CADCAM) full denture. It is a new system for the manufacture of removable dentures. Digital denture systems are exclusively designed software and ideally coordinated materials, combined with well- defined manufacturing strategies, and provide results of a consistently high quality. Aim: The aim of this study was to assess the awareness of digital denture systems among dental students. Materials and Methods: A questionnaire was prepared and circulated for a sample size of 100 students to analyze awareness of digital dentures systems among dental students. The questionnaire consisted of ten standardized questions. This was a survey-based research which had questionnaire prepared and was circulated among the dental college students through SurveyPlanet in social media. The results were obtained and were statistically analyzed. Results: The results were statistically analyzed and interpreted that 56.7% said all restorations, implants, and orthodontic appliances which can be done by CADCAM. About 70% said that they are aware of treatment using digital denture system. About 66.7% were aware of CADCAM crowns. About 43.3% were aware of digital processing of metal prostheses. Conclusion: From the survey, we conclude that students are aware of digital denture systems as CADCAM dentures are the reduced clinical chair time and the number of visits. Digital dentures are significantly high retention and more favorable clinical outcomes. CAD is widely used technology in the field of prosthodontics.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004912
Title: The effect of severe caries on the quality of life in young children: A cross-sectional study
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, - 600 077, Tamil Nadu, India.
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Background: Early childhood caries (ECC) is a relatively new term that encompasses all dental caries occurring in the primary dentition of young children from birth to 71 months of age. Over the past 40 years, this pattern of disease has been referred to as labial caries, caries of incisors, rampant caries, nursing bottle caries, and baby bottle tooth decay. ECC is defined as the presence of 1 or more decayed (noncavitated or cavitated lesions), missing (due to caries), or filled surfaces in any primary tooth. Aim: The aim of the study is to assess the possible effects of extensive dental caries on the quality of life (QOL) among young children. Materials and Methods: A questionnaire-based study was conducted among the parents to assess the possible changes in the living quality of their children with extensive caries. The study consisted of 100 children-parent pairs. The inclusion criteria consisted of parents with 1–10 years-old children from both sexes, with severe caries in the primary dentition. The exclusion criteria consisted of children with any debilitating systemic diseases or congenital syndromes. Results: The results indicated that of 100 children were participating in the study in which a majority of 74% of children experienced dental pain and 26% of children does not experience any dental pain. When asked about the consumption of food 70% of children have difficulty in eating whereas 30% of children did not have any problem while eating. About 54% of children have difficulty in drinking, whereas 46% of children did not have any problem while drinking. About 52% of children felt difficult in pronouncing words and 48% said that they did not experience any difficulty while speaking. Conclusion: From our study, we conclude that extensive caries among young children has a great impact on their QOL. The majority of parents feels that the major parameters which get affected due to extensive caries are trouble in sleeping, irritability and frustrated feeling, and difficultly in eating. Hence, it is very important that extensive caries in younger age should be considered as a serious factor and proper treatment should be initiated at the earliest.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004913
Title: A retrospective study of the radiographic bone formation in patients after indirect sinus lift using transcrestal osteotomy with simultaneous implant placement in tenting fashion
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nad
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Background: The placement of dental implants has revolutionized the restoration and management of the edentulous posterior maxilla with a fixed prosthesis. Augmentation of the bone volume by the elevation of the sinus membrane allows the placement of dental implants in atrophic maxillary ridges. Aim: The aim of this study was to retrospectively evaluate the amount of bone height gained using the transcrestal approach for sinus lift using osteotomes along with simultaneous placement of implants in our institution. Materials and Methods: Records of the past 2-year period (2014–2016) of partially edentulous patients reviewed in Saveetha Dental College were scanned to obtain records of patients who underwent implant placement to replace missing teeth in posterior edentulous maxillary region with deficient vertical bone height. The inclusion criteria being the sinus lift procedure had been carried out without the use of any graft material. The average follow-up time was 6–12 months. Cone-beam computed tomography (CBCT) evaluation pre-operative records were procured and the post-operative CBCT was taken. Bone height from the sinus floor to the bone crest was measured at the same site. Statistical Analysis Used: Paired t-test. Results: A total of 42 patients were shortlisted. Of these patients, 35 patients were identified as cases indicated for indirect sinus lift and they received 45 implants. All the implants used were 3.5 or 4.5 mm in diameter and 10.5, 11, or 13 mm in length. The cumulative survival rate of the implants was 97.78%. The average bone height, considered from the alveolar crest to the bottom of the implant, at the time of implant positioning was 6.79 mm ± 1.35 mm. The measured average bone height at the 6-month follow-up appointment was 11.4 mm ± 0.88 mm, which was highly significant (P < 0.05). Conclusion: Transcrestal osteotomy with implants used to tent the sinus membrane without additional graft material can show a significant mean bone height gain of 4.6 mm.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004914
Title: Awareness of metal toxicity caused by dental restorative materials among dental students – A survey
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: The metal toxicity caused by mercury amalgams from the dental restorative materials not only caused problems in pulp and oral cavity but also problems such as mood disorders such as anxiety, depression, and insomnia, autoimmune diseases such as Alzheimer’s and diabetes, and reproductive disorders such as low sperm count, infertility, premenstrual syndrome, genital tract problems, spontaneous abortions, birth defects, and learning disabilities in children. Aim: The aim of this survey is to check the awareness of metal toxicity caused by dental restorative materials. Materials and Methods: A questionnaire to test the awareness of the metal toxicity caused by dental restorative materials among dental students was prepared and given to dental students by an online survey through SurveyPlanet. The further results obtained were statistically analyzed. Results: About 68% of the participants are aware of mercury toxicity, 74% of the participants were aware of the side effects of amalgam vapors, and 39% are aware of preventive measures to reduce mercury toxicity. Conclusion: Although the dentists possess basic awareness about mercury toxicity, to keep up with the current trends, more knowledge is required on their part.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004915
Title: Awareness about orthodontic aligners among general population in Chennai, Tamil Nadu
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Background: Orthodontic treatment plays an important role in improving the quality of life and also to bring physical, psychological, and social changes. The major advantages of orthodontic treatment are to improve the physical function, prevention of tissue damage, and correction of esthetic component. Clear orthodontic aligners are used to straighten a patient’s teeth without the use of wires and brackets of traditional braces. Aim: This study aims to evaluate the awareness of orthodontic aligners among general population of age group 18–30 in Chennai, Tamil Nadu. Methodology: A cross-sectional survey was conducted among 100 individuals of age group 18–30 years. An online questionnaire was prepared using the Google Forms with 11 questions. The responses were collected and analyzed, the results were presented in the descriptive charts. Results: From our study, 67% of the total population were aware of the orthodontic aligners and 45% think that spacing can be corrected by orthodontic aligners. About 43% thinks that orthodontic aligners are not painful than conventional braces, followed by 27% of the population thinks that orthodontic aligners may be more painful than conventional braces, 21% thinks that orthodontic aligners are more painful than conventional braces, and 9% have no idea. Conclusion: From our study, we conclude that though the population were moderately aware of the clear aligners, they lack knowledge regarding when to choose clear aligners for their orthodontic treatment.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004916
Title: Awareness of polycystic ovarian syndrome in the female dental students among Chennai population
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Introduction: Polycystic ovarian syndrome (PCOD) is one of the most common reproductive and metabolic disorders seen among women of reproducible age. It occurs when there is an imbalance in the levels of female hormones and accumulation of multiple cysts in the ovaries. PCOD causes disruption in the menstrual cycle that typically begins during the onset of puberty. This is accompanied by lack of ovulation, leading to infertility, complications in getting pregnant, and reduces in insulin resistance level. Aim: This study aims to assess the level of the awareness of PCOD among the female dental students. Materials and Methods: A cross-sectional survey was distributed among 100 female dentists between 18 and 25 years of age from various government and private dental colleges in Chennai through the Google Forms app. The questionnaire consisted of 13 closed-ended questions which were formulated for checking whether the students are well aware of PCOD. Results: It was observed that majority of the female students have a vague idea about PCOD as only 29.29% of the students were aware of how PCOD develops. Conclusion: There is a high need for awareness of the PCOD among the female dentists. Early diagnosis and its treatment will help to improve the quality of their lives and thereby preventing various future health hazards.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004918
Title: Awareness on various periapical surgical methods among dental students
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Velappanchavadi, Chennai - 6
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Background: Apical surgery is considered a standard oral surgical procedure. It is often a last resort to surgically maintain a tooth with a periapical lesion that cannot be managed with conventional endodontic (re-)treatment. The main goal of apical surgery is to prevent bacterial leakage from the root-canal system into the periradicular tissues by placing a tight root-end filling following root-end resection. Hence, this study is done to assess the knowledge of dental students on various periapical surgical methods. Aim: The aim of the study is to assess the knowledge on various periapical surgical procedures among dental students. Materials and Methods: The questionnaire was self-formulated and was delivered by hand and collected on completion. The medium for answering the questionnaire was English. All the responses were kept anonymous. The questionnaire contained 15 questions which were framed to assess the knowledge, attitude, and practice on denture magnets among dental practitioners. The questions were related to types of periapical surgical procedures, indications, contraindications, etc. One hundred students were randomly selected to complete the questionnaire. The responses to each of the questions were entered into Microsoft Excel sheet and summarized through the pie chart. Results: Majority of the students, i.e., 56% of them were aware of periradicular surgery, but very few 21% and 23% of them were aware of corrective and fistulative surgery, respectively. About 7% of them were aware of cortical trephination under fistulative surgery. Under premedications administered during periapical surgery, 68% were aware of amoxicillin and many of them were unaware of valium and clindamycin. The majority of them were aware of the indications and contraindications of periapical surgery. Conclusion: This survey shows that the dental students have a fairly rough knowledge about various periapical surgical procedures. Yet some of them were unaware of cortical trephination and decompression procedures. Most of them had good knowledge regarding the flap designs used, but they did not have enough knowledge about various premedications used other than amoxicillin. Hence, it is important to educate them regarding all the indications, contraindications, types of procedures, thereby creating awareness among dental students, which will be useful for the students in their clinical practice.

Journal: Drug Invention Today , Volume: 14, Issue: March
Article Id: JPRS-P'Col-00004919
Title: Perception of their own smile among dental students
Category: Pharmacology
Section: Research Article
Author Affiliation: Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Velappanchavadi, Chennai - 6
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Introduction: A smile is a voluntary facial expression indicating happiness, pleasure, and greeting. It is rightly quoted that a smile is the prettiest thing that can be worn. A person that is smiling always seems more welcoming than a person that is not smiling. A smile also reflects on what the opposite person perceives about yourself. Materials and Methods: This was a questionnaire-based study. The questionnaire was distributed among 100 dental students. It consisted of 11 questions. These questions were framed to understand if the students were conscious about their smile, how people perceived their own smile and if they desired a better smile or were satisfied. The results obtained from this questionnaire-based study were studied and analyzed and a conclusion was drawn. Results: The results of the study revealed 11% of the people hide their smiles. About 51% of the people were not satisfied with the color of their teeth. It was observed that 51% of the population desired a better smile. Conclusion: This study concluded to dental students had concerns with their smiles, and they were willing to undergo treatments to correct their own smiles.