Drug Invention Today
ISSN NO: 0975-7619
Drug Invention Today (DIT) was first published in 2009 by JPR Solutions. It is a journal, which publishes reviews, research papers and short communications . 
• Novel Drug Delivery Systems • Nanotechnology & Nanomedicine • Biotechnology related pharmaceutical technology • Polymeric bio-conjugates • Biological macromolecules • Biomaterials • Drug Information • Drug discovery/development • Screening of drugs from natural & synthetic origins • Novel therapeutic strategies • Combinatorial chemistry and parallel synthesis • Clinical trials • Case Reports
 Impact FactorTM ( India ) = 0.897 as on date (08.05.2017)
  Scopus Indexed ( link http://www.scimagojr.com/journalsearch.php?q=21100202909&tip=sid&clean=0)
Journal Metrics for this   Drug Invention Today (Source ID: 21100202909): 2014 (SNIP) Source Normalized Impact Per Paper : 0.402; SCImago Journal Rank (SJR):0.301; Impact Per Publication : 0.517 (Top level : Life Science)
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Manuscripts Published

Journal: Drug Invention Today , Volume: 2, Issue: May
Article Id: JPRS-D(DD)-0000900
Title: Formulation and evaluation of topical gel of diclofenac sodium using different polymers
Category: Drug (Discovery/Development)
Section: Research Article
Country: India
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A wide choice of vehicles ranging from solids to semisolids form has been used for skin care and topical treatment of dermatological disease, High molecular weight water soluble polymers of Hydroxypropyl methylcellulose (HPMC), Carbapol 934P, Sodium alginate that possess very high viscosity, transparency, film forming properties at low concentration, are reported to useful in formation of gel. In the present investigation Diclofenac sodium gels were prepared for topical drug delivery by using different concentration of HPMC, Sodium alginate, Carbapol 934P, with an objective to increase transparency and spreadability. From the study it was concluded that HPMC gel containing Diclofenac sodium showed good consistency, homogeneity, spreadability and stability and has wider prospect for topical preparations as compared to Sodium alginate, Carbapol 934P gel containing Diclofenac sodium.

Journal: Drug Invention Today , Volume: 2, Issue: May
Article Id: JPRS-D(DD)-0000934
Title: Multiparticlate drug delivery systems : Pellet & pelletization technique
Category: Drug (Discovery/Development)
Section: Review Article
Country: India
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The present study aims at discussing the potential advantages of multiple unit dosage forms (pellets etc.) over the single unit dosage forms (Tablets).Review deals with the pellet and its ideal properties. The theory behind the pellet formation and its growth mechanism. There are various types of pelletization techniques like spheronization and extrusion, pelletization by layering, pelletization by solution layering & direct pelletization. The advantages, disadvantages & various applications of above mentioned techniques. Spheronization and extrusion, pelletization by layering are most widely used techniques. It also deals with novel mini tablet system and its processing for formulation. The different available marketed pellets and different excipients used in the pellet formulation are also discussed.

Journal: Drug Invention Today , Volume: 2, Issue: May
Article Id: JPRS-ADRS-0000935
Title: Review on Stereospermum suaveolens DC : A Potential Herb
Category: Ayurvedic Drugs Related Study
Section: Review Article
Country: India
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Plants have been an exemplary source of medicine. Ayurveda and other Indian literature mention the use of plants in treatment of various human ailments. India has about 45 000 plant species and among them, several thousands have been claimed to possess medicinal properties. Research conducted in last few decades on plants mentioned in ancient literature or used traditionally for diseases. Stereospermum suaveolens are known for their antimicrobial, antiprotozoal, and anti-inflammatory, puerperal fevers and affections of the brain. The present paper deals with the Phytochemistry and Pharmacological action of the plant Stereospermum suaveolens.

Journal: Drug Invention Today , Volume: 2, Issue: May
Article Id: JPRS-PS-0000936
Title: Impact of Helicobacter pylori on the prevalence of gastroduodenal diseases
Category: Pharmacological Screening
Section: Review Article
Country: India
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Helicobacter pylori is a virulent bacterium that colonizes in the protective mucous layer of human stomach. It is responsible for majority of gastric diseases such as peptic ulcers, gastro-oesophageal reflux diseases, chronic gastritis etc. Infection caused by this bacterium is one of the most common clinical setback occurring worldwide especially in the developing nations. The current article is focused on various aspects like structural characteristics, epidemiological features, routes of transmission and recent management strategies. Significant research findings of this infectious organism along with several pharmacotherapeutic vistas have also been discussed.

Journal: Drug Invention Today , Volume: 2, Issue: May
Article Id: JPRS-ADRS-0000937
Title: A review on Rubia cordifolia: Its phyto constituents and therapeutic uses
Category: Ayurvedic Drugs Related Study
Section: Review Article
Country: India
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Rubia cordifolia (Rubiaceae) is also known as, Manjishtha, Indian madder known to contain substantial amounts of anthraquinones, especially in the roots which is responsible for anti-tumor, anti-inflammatory, urinary disorders, antistress antimicrobial, hepatoprotective, radio protective, and anticancer, antimicrobial, antifungal, hypotensive, analgesic, antimalarial, antioxidant, antileukemic and mutagenic functions, immunomodulatory, anti-inflammatory and antioxidant activity. The plant contains substantial amounts of anthraquinones, especially in the roots, which is responsible for its pharmacological activity. The presented review summarizes the information concerning the pharmacological, phytochemistry, biological activity of the Rubia cordifolia.

Journal: Drug Invention Today , Volume: 2, Issue: May
Article Id: JPRS-D(DD)-0000938
Title: Formulation and evaluation of matrix tablets of acarbose
Category: Drug (Discovery/Development)
Section: Research Article
Country: India
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Monolithic matrix tablet of Acarbose were formulated as controlled release tablets employing Hydroxypropyl methylcellulose and Eudragit in different concentration and combination, and sustained release behavior of the fabricated tablets were investigated. controlled released matrix tablets containing 350 mg Acarbose were developed using different drug : polymers combination. Tablet prepared by direct compression method were subjected to physical characterization. Formulation was optimized on the basis of acceptable properties and in-vitro drug release.In-vitro drug release was carried out using USP Type II at 50 rpm in 900 ml of acidic dissolution medium (pH 1.2) for 1hr, followed by 900 ml alkaline dissolution medium (pH 7.4) upto 12 hr. Standard curve and withdrawal samples were analyzed in UV-Vis spectrophotometery 625nm with alkaline potassium permagnate as coloring agent. formulations F1, F2, F3 wherein hydroxypropyl methylcellulose K 100 M was employed, it was found that increasing the concentration of the polymer resulted in linearization of drug release curve and formulation F3 gave satisfactory drug release pattern. Formulations F4, F5, F6 containing Eudragit S-100 showed quite non-linearity in drug release. The drug release rate was strongly influenced by the type of polymer and concentration of polymer. To analyze the release mechanism zero order, Higuchi model and Kosmeyer -Peppa’s model were used. The use of simplified methodology is demonstrated to evolve unified mathematical model.