Inter. J. of Chemical and Analytical Science
ISSN NO: 0976-1209
International Journal of Chemical and Analytical Science (IJCAS) is a international journal which publishes high quality original research articles, reviews, short communications, and case reports that contribute significantly to the advancement of the scientific knowledge in the following categories:
  • PHARMACEUTICAL CHEMISTRY:
    • Synthesis and biological studies.
    • QSAR.
    • Novel drug design.
    • Rational drug design combinatorial and parallel synthesis.
    • Estimation of drug.
    • Method developments.
    • Analysis of various pharmaceutical drugs.
    PHARMACEUTICAL ANALYSIS:
    • Medicinal chemistry
    • Organic and synthetic chemistry
    • Natural products chemistry
It's online copy circulated to all bonafide members of JPR Solutions. The Editorial Board of IJCAS comprises of eminent scientists and pharmacists from reputed institutions worldwide.
Impact Factor TM ( India ) = 0.918 as on date (12.03.2018)

Manuscripts Published

Journal: Inter. J. of Chemical and Analytical Science, Volume: 1, Issue: July
Article Id: JPRS-NPs-0000357
Title: Evaluation and Expression of Uncertainty in the Measurement of Iodine Value in Mustard Oil
Category: Natural Products
Section: Research Article
Country: India
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The significance of uncertainty must be known as the performer of the test to eliminate any error which carrying out testing as it is a part of measurement. The uncertainty of measurement defines the rate of lowest possible deviation from the true value and it is also defines the level of confidence. Quality of analysis has assumed great significance in view of the fact that measurement provides the very basis of all control actions. The analysis process is at best an estimate of or approximation to the true value. The uncertainty of measurement is a right tool, associated with the result of a measurement that characterizes the dispersion of the true value which could reasonably be attributed to the measurand.

Journal: Inter. J. of Chemical and Analytical Science, Volume: 1, Issue: July
Article Id: JPRS-DD-0000358
Title: Development and characterization of niosomal drug delivery of α-tocopherol
Category: Drug Delivery
Section: Research Article
Country: India
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The present study is an aim to overall improvement in the efficacy, reduced toxicity and enhancement of therapeutic index of niosome carrying α-tocopherol.Niosome were prepared by reverse phase evaporation method using span and tween (20 and/or 60).The preparations were characterize with respect to size reduction, entrapment efficiency, in-vitro drug release profile and stability under specific conditions. The diameter of niosomes ranges from 1-5μm with discrete and round in shape.The percent entrapment efficiency of the vesicles was found to be 67.84 %, 61.17%, 75.13% and 79.63% for F1, F2, F3 and F4 respectively. Highly cumulative release was observed with 81.78 % for span 20, 75.92% for span 60, 96.01% for tween 20 and 92.35 % for tween 60 respectively. Stability studies proved that optimum storage condition for niosomes was found to be 40C.

Journal: Inter. J. of Chemical and Analytical Science, Volume: 1, Issue: July
Article Id: JPRS-PSPA-0000359
Title: In vitro antibiotic activity of volatile oils of Carum carvi & Coriandrum sativum
Category: Phytochemical Study and Pharmacological Activity
Section: Research Article
Country: India
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The antimicrobial activity of Volatile Oils isolated from Carum Carvi and Coriandrum Sativum were studied. The isolated Volatile Oils in varying concentrations were studied against Pseudomonas Aeruginosa and Proteus Vulgaris, by paper disc diffusion method, using Streptomycin as standard drug. The result indicated that both Carum Carvi and Coriandrum Sativum has antimicrobial potential and were active against Pseudomonous Aeruginosa selectively, while both oils were ineffective against Proteus Vulgaris.

Journal: Inter. J. of Chemical and Analytical Science, Volume: 1, Issue: July
Article Id: JPRS-AC-0000360
Title: A Validated Spectrophotometric methods for the determination of Ziprasidone as Hydrochloride in Bulk and pharmaceutical formulations
Category: Analytical Chemistry
Section: Research Article
Country: India
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Three simple, sensitive, selective and accurate Spectrophotometric methods (M1 to M 3) for the determination of Ziprasidone Hydrochloride (ZPD.HCl) in bulk drug and pharmaceutical formulations (tablets) have been described. Three individual methods are based on the charge transfer complex formation (M1), Inner salt formation (M2) and Precipitation/complex formation reaction (M3) of drug with different reagents to form colored chromogens exhibiting lmax 540 (M1), 580 (M2) and 470 (M3) nm respectively. The results of analysis for the three methods have been validated statistically and by recovery studies. The results are compared with those obtained using UV Spectrophotometric method in isopropyl alcohol at 229 nm.

Journal: Inter. J. of Chemical and Analytical Science, Volume: 1, Issue: July
Article Id: JPRS-AC-0000361
Title: New Aurum Coupling Reaction for Visible Spectrophotometric Determination of Tolterodine Tartrate in Pharmaceutical Preparations
Category: Analytical Chemistry
Section: Research Article
Country: India
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Simple, rapid and sensitive spectrophotometric procedures were developed for the analysis of Tolterodine Tartrate (TT) in pure form as well as in pharmaceutical formulations. The methods are based on the reaction of TT with gold (III) chloride in the pH range 1.0 – 5.0 forming violet colored complex solution, showing absorption maxima at 540 nm. The linear plot indicates that Beer’s law is obeyed in the range of 10 – 90 μg/ml of tolterodine tartrate. The molar absorptivity and Sandell’s sensitivity are 5.43 x 103 l mol-1 cm-1 and 0.0876 μg/cm2 respectively. The standard deviation of the method for ten determinations of 20 μg/ml of tolterodine tartrate is 9.49 x 10-4. The correlation coefficient (?) of the experimental data of the calibration plot is 0.9989. The effective range of concentration for accurate determination of tolterodine tartrate as ascertained from Ringbom’s plot and it is 20 – 90 μg/ml.