Inter. J. of Chemical and Analytical Science
ISSN NO: 0976-1209
International Journal of Chemical and Analytical Science (IJCAS) is a international journal which publishes high quality original research articles, reviews, short communications, and case reports that contribute significantly to the advancement of the scientific knowledge in the following categories:
    • Synthesis and biological studies.
    • QSAR.
    • Novel drug design.
    • Rational drug design combinatorial and parallel synthesis.
    • Estimation of drug.
    • Method developments.
    • Analysis of various pharmaceutical drugs.
    • Medicinal chemistry
    • Organic and synthetic chemistry
    • Natural products chemistry
It's online copy circulated to all bonafide members of JPR Solutions. The Editorial Board of IJCAS comprises of eminent scientists and pharmacists from reputed institutions worldwide.
Impact Factor TM ( India ) = 0.918 as on date (12.03.2018)

Manuscripts Published

Journal: Inter. J. of Chemical and Analytical Science, Volume: 2, Issue: February
Article Id: JPRS-NPs-0000396
Title: Soxhlet Extraction of Neem seed (Azadirachta indica A. Juss) Using Hexane as a Solvent.
Category: Natural Products
Section: Research Article
Author Affiliation: Faculty, Jawaharlal Darda Institute of Engineering and Technology, Yavatmal(MS), India.
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This work proposed the Soxhlet extraction of Neem oil from Neem seeds (Azadirachta indica A. Juss) using hexane as solvent. Effects of particle size, temperature, and residential time on the extraction parameters were studied. Neem oil was extracted using hexane solvent with ratio of neem seed powder weight to solvent volume of 1:5. Here we have studied the yield of oil. Here, the control mechanism for soxhlet extraction of Neem oil in hexane is mass transfer, and we studied the yield data of Neem oil extraction by using Soxhlet Apparatus. Based on the analysis, showed that decreasing particle size increases the yield of oil and increase in temperature increases the yield of oil. We got the maximum yield of oil of 20ml from 50gm of raw material at a temperature of 650C and 0.6 mm particle size. As the time of contact increases the yield of oil also increases up to optimum time of contact.

Journal: Inter. J. of Chemical and Analytical Science, Volume: 2, Issue: February
Article Id: JPRS-PSPA-0000397
Title: Assessment of Medicinal Potentials of Cleome viscosa L. Methanol Extract
Category: Phytochemical Study and Pharmacological Activity
Section: Research Article
Author Affiliation: Department of Microbiology, Acharya Nagarjuna University, AP, India
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The antimicrobial activity of methanol extract obtained from Cleome viscosa L. was tested against 4 bacterial species (Erwinia carotova, Pseudomonas
marginalis, Pseudomonas syringe and Xanthomonas campestris) and 10 fungal species of (Alternaria alternate, Aspergillus flavus, Aspergillus niger, Acremonium
strictum, Bipolaris bicolor, Fusarium oxysporium, Pencillium expansum, Rhizoctina solani, Tiarosporella phaseolina and Ustilago maydis) plant pathogens. Better antibacterial activity was observed with the extract showed maximum activity against Erwinia carotova. Among different fungi tested Tiarosporella phaseolina and Alternaria alternate were found to be more sensitive to plant methanol crude extract. The antimicrobial assay was performed by agar well diffusion method. Recent investigations have shown that the antioxidant properties of plants could be correlated with oxidative stress defense and different human diseases. In this respect flavonoids and other polyphenolic compounds have gained the greatest attention. The plant extract was tested for Ferric reducing ability of Plasma Assay (FRAP) and total phenol content. For antimicrobial activities tested, the extract was subjected to its effectiveness against both
bacteria and fungi. The zones of inhibition produced by the crude methanol extract against selected phytopathogens were measured and compared with those of standard antibiotics Streptomycin for bacteria and Bavistin for fungi. The present study was undertaken to evaluate the in vitro antimicrobial and antioxidant activities of methanol extract of whole plant of Cleome viscosa. The results of present study revealed that C. viscosa whole plant might be explored as viable source of antimicrobial and antioxidant agent.