Journal: Journal of Pharmacy Research

Article Id: JPRS-MB-00001239
Title: Antimicrobial activity of some medicinal plant extracts and its synergistic interaction with some antibiotics
Category: Microbiology
Section: Research Article
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    Background: The synergism is a new concept in developing agents for antimicrobial therapy. The new approach is combination therapy i. e. combination of different plant extracts with antibiotics against resistant microorganisms which may lead to new ways of treating infectious diseases. Synergistic interaction means when two agents are combined together and they exert an inhibitory effect that is greater than the sum of their individual effects. The present study focuses on the in vitro antimicrobial activity and synergistic activity of various parts of different plants such Aegle marmelos, Annona squamosa, Citrus limon, Piper betle, and Azadiracta indica. Material and Method: The synergistic antimicrobial activity was evaluated by the Agar disc diffusion method against Gram- positive, Gram -negative and Fungi. Result and Discussion: All the plant extracts with Gentamicin showed good synergistic antibacterial activity against Gram-positive and Gram-negative bacteria. All the plant extracts with Ketoconazol showed good synergistic antifungal activity against fungi. Conclusion: Hence, these plants extracts can be used as good medicinal sources in combination with antibiotics to treat infectious diseases.

    Cite this article as:Hemali Padalia, Anjali Trivedi, Sumitra Chanda,Antimicrobial activity of some medicinal plant extracts and its synergistic interaction with some antibiotics, Journal of Pharmacy Research 2016,10(5),211-220.

     

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    Author(s) Name:

    Hemali Padalia, Anjali Trivedi, Sumitra Chanda*

    Affiliation(s) Name:

    Phytochemical, Pharmacological and Microbiological laboratory, Department of Biosciences, Saurashtra University, Rajkot, India, 360005.

    *Corresponding author.
    Dr. Sumitra Chanda
    Phytochemical, Pharmacological and
    Microbiological laboratory,
    Department of Biosciences,
    Saurashtra University,
    Rajkot, India, 360005

    Received on:14-02-2016; Revised on: 20-03-2016; Accepted on: 25-04-2016

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    Author:

    Hemali Padalia, Anjali Trivedi, Sumitra Chanda*

    Title:Antimicrobial activity of some medicinal plant extracts and its synergistic interaction with some antibiotics
    Journal:Journal of Pharmacy Research
    Vol(issue):10 (May)
    Year:2016
    Page No: (211-220)
  • Experimental Methods Keywords

    Methodology:Antimicrobial activity, Synergistic activity
    Research Materials:Medicinal plants

Keywords

Medicinal plants Antibiotics Antimicrobial activity Synergistic activity

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