Article Id:JPRS-P'Col-00001343 Title:Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin-induced diabetic rats Category:Pharmacology Section:Research Article
Abstract
Audio Abstract
Authors
Pdf File
Citation
My Reference
Methodology
Abstract
To evaluate the hypoglycemic activity of methanolic extract of lantana camara linn fruits in normal and streptozotocin induced diabetic rats.Material and methods: Methanolic extract of lantana camara linn fruits were orally tested at the dose of 100 and 200 mg/kg forhypoglycemic activity for normal and streptozotocin induced diabetic rats. In addition changing in body weight, HbA1c, assessed in the methanol-treated diabetic rats, were compared with diabetic control and normal animals. Histopathological observations during 21 days treatment were also evaluated.Statistical analysis:Analysis of Variance (ANOVA) followed by Multiple comparison student two-tail‘t’ test was used for statistical analysis of collected data. Differences were considered significant at p
1Department of Pharmaceutical Chemistry, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India 2Department of Phytopharmacy and Phytomedicine, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India. 3Department of Pharmaceutical Analysis, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India. 4Department of Pharmacy Practice, J.K.K.Nataraja College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India.
*Corresponding author. T.Venkatachalam, M.Pharm.,(Ph.D.,) Assistant Professor Department of Pharmaceutical chemistry, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India.
Received on: 02-02-2011; Revised on: 08-03-2011; Accepted on:12-04-2011