Journal: Journal of Pharmacy Research
Title: Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin-induced diabetic rats
Category: Pharmacology
Section: Research Article
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Abstract
To evaluate the hypoglycemic activity of methanolic extract of lantana camara linn fruits in normal and streptozotocin induced diabetic rats.Material and methods: Methanolic extract of lantana camara linn fruits were orally tested at the dose of 100 and 200 mg/kg forhypoglycemic activity for normal and streptozotocin induced diabetic rats. In addition changing in body weight, HbA1c, assessed in the methanol-treated diabetic rats, were compared with diabetic control and normal animals. Histopathological observations during 21 days treatment were also evaluated.Statistical analysis:Analysis of Variance (ANOVA) followed by Multiple comparison student two-tail‘t’ test was used for statistical analysis of collected data. Differences were considered significant at p
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About the authors and Affiliations
Author(s) Name: T.Venkatachalam1*, V.Kishor Kumar2, P.Kalai Selvi3, Avinash O. Maske1, V.Anbarasan1, P.Siva Kumar4
Affiliation(s) Name: 1Department of Pharmaceutical Chemistry, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India
2Department of Phytopharmacy and Phytomedicine, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India.
3Department of Pharmaceutical Analysis, J.K.K.Munirajah Medical Research Foundation College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India.
4Department of Pharmacy Practice, J.K.K.Nataraja College of Pharmacy, B. Komarapalayam - 638183, Namakkal, Tamil Nadu, India.*Corresponding author.
T.Venkatachalam, M.Pharm.,(Ph.D.,)
Assistant Professor
Department of Pharmaceutical chemistry,
J.K.K.Munirajah Medical Research Foundation College of Pharmacy,
B. Komarapalayam - 638183, Namakkal,
Tamil Nadu, India.
Received on: 02-02-2011; Revised on: 08-03-2011; Accepted on:12-04-2011-
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Author: T.Venkatachalam1*, V.Kishor Kumar2, P.Kalai Selvi3, Avinash O. Maske1, V.Anbarasan1, P.Siva Kumar4
Title: Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin-induced diabetic rats Journal: Journal of Pharmacy Research Vol(issue): 4 (May) Year: 2011 Page No: (1550-1552) -
Experimental Methods Keywords
Methodology: Antiserotonergic activity Research Materials: Lantana camara
Keywords
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