Article Id:JPRS-PC-00001379 Title:Benzimidazole: A Valuable Insight Into The Recent Advances and Biological Activities Category:Pharmaceutical Chemistry Section:Review Article
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Considerable research works have been done on benzimidazole and their derivatives to evaluate their antibacterial, antiviral, anticancer, anticonvulsant, antihistaminic, anthelminitic and antidepressant activity and some of works have provided very promising results in antiasthamatic and antidiabetic activity. A wide variety of benzimidazole derivatives have been described for their chemotherapeutic importance. However there is a great need to study the various pharmacological actions derived from benzimidazole nucleus through research work. This account gives an overview of the benzimidazole based system and their relevance in medicinal chemistry.However there is a great need to study the various pharmacological actions derived from benzimidazole nucleus through research work. The chemical reactions of benzimidazole with various reagents resulting in substituted benzimidazole derivatives which have a diverse biological importance.
Asif Husain1, M.M. Varshney2, Mohd Rashid1*, Ravinesh Mishra1, Afroz Akhter1
Affiliation(s) Name:
1.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi-110062 (INDIA). 2.Dept of Pharmacy, Raj Kumar Goel institute of Technology, 5th km stone Delhi-Meerut road, Ghaziabad (U.P.), (INDIA).
*Corresponding author. Mohd Rashid, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard University, Hamdard Nagar, New Delhi-110062, India.
Received on: 10-11-2010; Revised on: 15-12-2010; Accepted on:09-01-2011