Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-00001389
Title: Transdermal Drug Delivery Systems with major emphasis on Transdermal patches : A Review
Category: Pharmaceutics
Section: Review Article
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  • Abstract

    Due to the recent advances in this technology and as the incorporation of the drug to the site of action is done without rupturing the skin membrane, the transdermal route is becoming very widely accepted route of drug administration. When transdermal formulations are applied to the intact skin , they deliver the drug through the skin at a controlled rate to the systemic circulation. Any formulation like ointments , creams , gels can be used as transdermal formulations for a particular drug, after careful selection of the base and addition of the penetration enhancers . Transdermal patches are the best available TDDS systems which are applied on the surface of the skin to deliver a specific dose of medication through the skin to the blood stream, thus this review mostly revolves around TDDS patches. Various other methods used for drug transport to the blood through skin are Intophoresis, Electroporation, Ultrasound, Reverse electrporation, Photochemical wave etc which also come under TDDS. This review is an attempt to compile the relevant information and techniques under Transdermal Drug Delivery Systems (TDDS) along with the evaluation (in vitro and in vivo) of these. This review also includes recent advances in the field of TDDS. Authors have also made a comment on the limitations of TDDS, comparision of topical and TDDS and toxicity considerations of topical preparations.

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  • About the authors and Affiliations

    Author(s) Name:

    Meera C. Singh * ,Ajinkya S. Naik, S.D. Sawant

    Affiliation(s) Name:

    * Department of Pharmaceutics ,Sinhgad Technical Education Society’s Smt. Kashibai Navale College of Pharmacy, Pune 411048 ,Maharashtra , India.

    *Corresponding author.
    Mrs Meera Chadradatt Singh
    Assistant Professor in Pharmaceutics
    Sinhgad Technical Education Society’s Smt. Kashibai Navale College of
    Pharmacy, Kondhwa -Saswad Road ,Kondhwa [bk]
    Pune 411048 ,Maharashtra , India

    Received on: 14-06-2010; Revised on: 18-08-2010; Accepted on:19-09-2010

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    Meera C. Singh * ,Ajinkya S. Naik, S.D. Sawant

    Title:Transdermal Drug Delivery Systems with major emphasis on Transdermal patches : A Review
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (October)
    Page No: (2537-2543)
  • Experimental Methods Keywords

    Methodology:Transdermal Drug Delivery Systems (TDDS)
    Research Materials:synthetic Drugs


Transdermal Drug Delivery Systems (TDDS) Intophoresis Electroporation Ultrasound Reverse electrporation Photochemical wave in vitro and in vivo topical formulations

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