Article Id:JPRS-PC-00001390 Title:Synthesis,characterization and antimicrobial activity of Schiff bases of isatin and isatin derivatives Category:Pharmaceutical Chemistry Section:Research Article
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Several new Schiff’s base derivatives were prepared by the combination of Isatin and its prepared derivatives and Isoniazid in the presence of glacial acetic acid and ethanol. All the compounds were characterized by physical and spectral studies. The newly synthesized compounds were evaluated for their antimicrobial activities.
1Department of Prescription Audit, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India-110076 2Department of Pharmacology, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, 5th Mile, Tadong, Gangtok, E. Sikkim, India-737102 3Department of Pharmaceutical Chemistry, Dr. K.N Modi Institute of Pharmaceutical Education and Research, Modinagar, Ghaziabad, Uttar Pradesh India-201204
*Corresponding author. Sourabh Bhardwaj Clinical Pharmacist, Department of Prescription Audit, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India-110076.
Received on: 15-06-2010; Revised on: 18-08-2010; Accepted on:13-09-2010