Article Id:JPRS-P'Col-00001393 Title:Antiulcer activity of Methanolic extract of Acalypha indica Linn. (Euphorbiaceae) by PylorousLigture and Swim Stress Induced Ulceration Category:Pharmacology Section:Research Article
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Medicinal plants are nature’s gift to mankind. The plant kingdom holds many species containing substances of medicinal properties; the plant was used in folk medicine against pneumonia asthma and anthelminitic, diuretic, carminative, expectorant and emetic properties. The phytochemical investigation showed the presence of amino acids, proteins, alkaloids, steroids, flavonoids, gums and mucilage. The present study intended to evaluate the anti-ulcer activity was done in pylorus ligature and swim stressed induced ulcer in Wistar rats by using methanolic extract of Acalipha indica (MEAI). The MEAI showed significant reduction of gastric volume secretion, acidity and ulceration in pylorus legated and swim stressed rats at p
S. Kalimuthu*1, P. Rajesh2, V. Rajesh Kannan2, B. Balamurugan1, T.M. Chandrasekar1
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1Department of pharmaceutical technology, Anna University Tiruchirappalli, Tiruchirappalli-620024. 2Department of Microbiology, Bharathidasan University, Tiruchirappalli-620024.
*Corresponding author. P. Rajesh., (Ph.D.,) Doctoral Research Scholar, C/O, Dr. V. Rajesh Kannan, Ph.D., Assistant Professor, Department of Microbiology, Bharathidasan University, Tiruchirappalli-620024. Tamil Nadu.,India.
Received on: 15-06-2010; Revised on: 18-08-2010; Accepted on:13-09-2010