Journal: Journal of Pharmacy Research
Title: Anti ulcer activity of ethanolic extract of Drynaria quercifolia Linn. leaves
Category: Pharmacology
Section: Research Article
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Abstract
Objective: To evaluate the anti-ulcer activity of etanolic extract of leaves of Drynaria quercifolia Linn. Materials and Methods: The etanolic extract of leaves of Drynaria quercifolia was investigated for its anti-ulcer activity against pylorus ligation and ethanol induced ulcer models in experimental rats at doses of 250 and 500 mg/kg body weight p.o. Results: The Aqueous extract of Drynaria quercifolia (250 mg/kg & 500 mg/kg) showed significant (P<0.05) reduction in gastric volume, free acidity and ulcer index as compared to control. Conclusion: This present study indicates that etanolic extract of Drynaria quercifolia have potential anti- ulcer activity in the both models. These results may further suggest that the extract was found to possess antiulcerogenic as well as ulcer healing properties, which might be due to its antisecretory activity.
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About the authors and Affiliations
Author(s) Name: D.Soni*, Jagan Mohan.K, Sai Goud.A, V.R.Krishna Raju.Mantena
Affiliation(s) Name: Department of Pharmacology, MNR College of Pharmacy, Sangareddy, Medak district, Andhra Pradesh, India.
*Corresponding author.
D. Soni
M.Pharm.
Department of Pharmacology,
MNR College of Pharmacy,
Sangareddy, Medak district,
Andhra Pradesh, India.Received on:20-09-2011; Revised on: 15-10-2011; Accepted on:10-12-2011
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Author: D.Soni*, Jagan Mohan.K, Sai Goud.A, V.R.Krishna Raju.Mantena
Title: Anti ulcer activity of ethanolic extract of Drynaria quercifolia Linn. leaves Journal: Journal of Pharmacy Research Vol(issue): 5 (January) Year: 2012 Page No: (117-119) -
Experimental Methods Keywords
Methodology: Anti ulcer activity-Pylorus ligation, Ethanol induced ulcer model, ulcer index. Research Materials: Drynaria quercifolia
Keywords
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