Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000146
Title: In vitro α-glucosidase and α-amylase inhibitory activity of psidium guajava extracts
Category: Pharmacology
Section: Research Article
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  • Abstract

    The objective of the present study was to determine the inhibitory activity of in vitro a-glucosidase and á-amylase using leaves extracts of Psidium guajava (PG) The leaves of PG were extracted with methanol (MEPG) and aqueous (AEPG). The extracts were analyzed for the in vitro α-glucosidase and α-amylase inhibition activity and total phenol content. The results show that methanolic extracts have α-glucosidase and α-amylase inhibitory activity with IC50 of 187.21μg/mL and 199.1μg/mL, respectively. Aqueous extract of PG have low α-glucosidase and α-amylase inhibitory activity. The total phenol contents of MEPG were higher than that of AEPG. MEPG is potential for diabetes mellitus management.

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    Author(s) Name:

    V. Sugantha Kumari1 and S. Khaleel Basha2*

    Affiliation(s) Name:

    1Department of Chemistry, Auxilium College, Vellore-632 006, India
    2*Department of Biochemistry, C. Abdul Hakeem College, Melvisharam-632 509, India. 

    *Corresponding author.
    Dr. S.Khaleel Basha
    Department of Biochemistry,
    C. Abdul Hakeem College,
    Melvisharam,-632509
    Vellore,India
    Received on:21-01-2014; Revised on: 11-02-2014; Accepted on:09-03-2014

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    Author:

    V. Sugantha Kumari1 and S. Khaleel Basha2*

    Title:In vitro α-glucosidase and α-amylase inhibitory activity of psidium guajava extracts
    Journal:Journal of Pharmacy Research
    Vol(issue):8 (March)
    Year:2014
    Page No: (349-351)
  • Experimental Methods Keywords

    Methodology:in vitro α-glucosidase and α-amylase inhibition activity
    Research Materials: P. guajava

Keywords

P. guajava extracts α-glucosidase α -amylase

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