Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-00001733
Title: Oral dissolving films of Celecoxib inclusion complexes using Musa paradisiaca as super disintegrant in treatment of Psoriatic arthritis
Category: Pharmaceutics
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Celecoxib is a poorly water soluble drug which is a selective COX-2 inhibitor used in treating Psoriatic arthritis. It shows poor dissolution and flow properties. So physical mixures of the drug using solubilizers like β CD were prepared in order to enhance its solubility and dissolution rate. Super disintegrant plays a vital role in increasing drug release. Musa paradisiaca, a natural excepient is used in this study as a super disintegrant. The aim of present study was to formulate oral dissolving films of Celecoxib using solubilizer and evaluate them for in vitro disintegration and dissolution rates. It was found that β CD had shown good impact on increasing solubility and dissolution rate. Drug excepient compatibility was studied by FTIR studies.

  • Abstract Audio

    Click Here

  • About the authors and Affiliations

    Author(s) Name:

    Padmini Iriventi*, N. Vishal Gupta

    Affiliation(s) Name:

    Department of Pharmaceutics, JSS College of Pharmacy, Jagadguru Sri Shivarathreeshwara University, Sri Shivarathrishwara Nagara, Mysuru-570015, India.

    *Corresponding author
    Padmini Iriventi
    Department of Pharmaceutics,
    JSS College of Pharmacy,
    Shivarathrishwara Nagara,
    Bannimantap,Mysuru 570015, India

    Received on:18-03-2017; Revised on: 22-04-2017; Accepted on: 24-05-2017

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Padmini Iriventi*, N. Vishal Gupta

    Title:Oral dissolving films of Celecoxib inclusion complexes using Musa paradisiaca as super disintegrant in treatment of Psoriatic arthritis
    Journal:Journal of Pharmacy Research
    Vol(issue):11 (May)
    Year:2017
    Page No: (517-521)
  • Experimental Methods Keywords

    Methodology:Oral dissolving films ,solubility, dissolution rate studies
    Research Materials:Musa paradisiaca, Celecoxib

Keywords

Celecoxib; Psoriatic arthritis; Musa paradisiaca; Oral dissolving film.

Our Services

Most Downloaded List