Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002673
Title: Antimicrobial activity of Allium cepa against bacteria causing enteric infection
Category: Pharmacology
Section: Research Article
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    Introduction: Allium is the largest and important representative genus of the Liliaceae family comprises 450 species. Onion (Allium cepa) is a bulbous plant widely cultivated in almost every country of the world. Bacteria commonly involved in enteric infection are Escherichia coli and Vibrio cholerae. Enteric infections are characterized by diarrhea, abdominal discomfort, nausea, and vomiting. The aim of the study is to evaluate the antimicrobial activity of A. cepa against bacteria causing enteric infection. Methods: The screening of antibacterial activity of extracts was carried out using the agar well diffusion method. The culture plates were allowed to stand on the working bench for 30 min for prediffusion and were then incubated in upright position at 37° C for 24 h. Standard antibiotic discs ciprofloxacin (30 mcg/disc) were used as positive control. Results: The extracts at different concentration exhibited antibacterial activity against all bacterial strains tested. The extract was more effective against E. coli with a zone of inhibition of 28 mm (at conc. 200/µg) and was least effective against Pseudomonas aeruginosa with zone of inhibition of 16 mm (at conc. 200 µg.). Staphylococcus aureus showed a zone of inhibition of 23 mm diameter (at conc. 200 µg.). Conclusion: We conclude that the extracts of A. cepa can be used as antimicrobial agent against bacteria causing enteric infections.

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    Author(s) Name:

    M. P. Induja, R. V. Geetha*

    Affiliation(s) Name:

    Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. V. Geetha, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    M. P. Induja, R. V. Geetha*

    Title:Antimicrobial activity of Allium cepa against bacteria causing enteric infection
    Journal:Drug Invention Today
    Vol(issue):10 (December)
    Year:2018
    Page No: (2489-2492)
  • Experimental Methods Keywords

    Methodology:Antimicrobial activity
    Research Materials:Allium cepa

Keywords

Allium cepa Escherichia coli Enteric infections Pseudomonas Staphylococcus aureus

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