Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002896
Title: Clinical and laboratory indicators in pregnant women with preeclampsia
Category: Pharmacology
Section: Research Article
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    Objectives: The objective of this study is to compare clinical and laboratory indicators in pregnant women with preeclampsia (PE) compared with women with physiological pregnancy. Materials and Methods: The study group included 459 women: 209 women with physiological pregnancy and 250 pregnant women with PE. We studied coagulogram data, biochemical blood analysis, and the level of systolic and diastolic blood pressure before and during pregnancy. Results: It was established that pregnant women with PE have higher blood pressure indicators than women without PE. The content of fibrinogen in the blood and the rate of thrombin time in pregnant women with PE are higher, and the prothrombin ratio, partial thromboplastin time, and the total protein content in the blood are lower compared to women without PE (P < 0.01). Conclusions: Thus, as a result of this study, significant associations of blood pressure and hemostasis in pregnant women with PE were established, compared with women with physiological pregnancy.

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    Author(s) Name:

    Oleg V. Golovchenko, Evgeny A. Reshetnikov*, Inna K. Aristova, Valentina, S. Orlova, Irina V. Batlutskaya, Evgeny N. Krikun

    Affiliation(s) Name:

    Department of Medical Biological Disciplines, Belgorod State University, Belgorod, 308015, 85, Pobeda Street, Russia

    *Corresponding author: Evgeny A. Reshetnikov, Belgorod State University, Belgorod, 308015, Pobeda Street, 85, Russia,

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    Author:

    Oleg V. Golovchenko, Evgeny A. Reshetnikov*, Inna K. Aristova, Valentina, S. Orlova, Irina V. Batlutskaya, Evgeny N. Krikun

    Title:Clinical and laboratory indicators in pregnant women with preeclampsia
    Journal:Drug Invention Today
    Vol(issue):10 (December [ Special Issue 4 ])
    Year:2018
    Page No: (3453-3455)
  • Experimental Methods Keywords

    Methodology:Arterial hypertension, Blood pressure, Preeclampsia, Pregnancy
    Research Materials:250 pregnant women with PE

Keywords

Arterial hypertension Blood pressure Preeclampsia Pregnancy

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