Journal: Drug Invention Today

Article Id: JPRS-PCS-00002904
Title: Liposomes as targeted drug delivery system: A review
Category: Pharmaceutics
Section: Research Article
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    Liposomes have drawn the attention of various biological researchers which act as potential carriers as well as targeted drug delivery system that would contain various bioactive molecules which have a wide range of therapeutic application. Liposomes are artificial spherical vesicles made up of phospholipids which are non-toxic in nature and cholesterol. They are known promising systems of novel drug delivery since it has a definite size, shape, and hydrophilic and hydrophobic property. Liposomes are made up of lipid body and subcellular components which resemble the structure of ribosomes in which active drug is encapsulated inside the vesicles. Liposome encapsulation is widely used in cosmetic and pharmaceutical industry where liposomes are used as curative promoters in the proposal if targeted drug delivery. They are the submicroscopic foams which act as the biological barrier against the saliva, stomach, alkaline juice of the intestine, bile, intestine flora as well as free radicals and also defended from oxidation and degradation. Phospholipid remains intact until all contents are dispatched to targeted site or organ. The main purpose is to increase therapeutic index and decrease side effects. In this review, the structure, classification, method of preparation, characterization, and applications are discussed below.

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    Author(s) Name:

    J. Monisha, V. Manimaran*, N. Damodharan

    Affiliation(s) Name:

    Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India

    *Corresponding author: V. Manimaran, Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India.

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    Author:

    J. Monisha, V. Manimaran*, N. Damodharan

    Title:Liposomes as targeted drug delivery system: A review
    Journal:Drug Invention Today
    Vol(issue):10 (December [ Special Issue 4 ])
    Year:2018
    Page No: (3488-3497)
  • Experimental Methods Keywords

    Methodology: targeted drug delivery system
    Research Materials:Liposome

Keywords

Bilayer Carriers Cell membrane Cholesterol Liposomes Phospholipids Surfactants

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