Journal: JPR:BioMedRx:An International Journal

Article Id: JPRS-BC-0000309
Title: Lipid profiles and marker enzymes in alcoholic hypertensive patients with/without diabetes
Category: Biochemistry
Section: Research Article
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    Background: Lipid profiles and Marker enzymes has been implicated in the progression of alcoholic hypertension and diabetic hypertension. Method: The lipid profiles and Marker enzymes of plasma were investigated in alcoholic hypertensive patients and alcoholic hypertensive patients with diabetes and compared with normal subjects. Results: A significant increase is observed in the levels of total cholesterol, LDL Cholesterol and VLDL Cholesterol, TG levels and TC/HDL ratio (P<0.05) in the alcoholic hypertensive patients with/without diabetes and the further increase in the levels of TG and TC/HDL ratio is significantly higher in alcoholic hypertensive patients with diabetes. HDL cholesterol levels significantly decrease in alcoholic hypertensive patients with/without diabetes and further decrease is noted in alcoholic hypertensive patients with diabetes as compared to alcoholic hypertensive patients without diabetes. The activities of AST, ALT increase significantly in alcoholic hypertensive patients with/without diabetes and a further increase is observed in alcoholic hypertensive patients with diabetes as compared to alcoholic hypertensive patients without diabetes. No significant difference is observed in the activities of CK-MB and electrolytes (Na+, K+ and Cl-] among the normal subjects, alcoholic hypertensive patients with/without diabetes. Conclusions: An increase the levels of TG, TC/HDL ratio and decreased the levels of HDL cholesterol were observed in alcoholic hypertensive patients with diabetes and a more pronounced increase in the activities of AST, ALT among marker enzymes.

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    Author(s) Name:

    Veerappan, RM and Malarvili T

    Affiliation(s) Name:

    Department of Biochemistry, Rajah Serfoji Govt College, Thanjavur Tamil Nadu,India.

    *Corresponding author.
    Veerappan, RM
    Department of Biochemistry, Rajah Serfoji Govt College, Thanjavur
    Tamil Nadu ,India


    Received on:11-01-2013; Revised on: 07-02-2013; Accepted on:25-03-2013

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    Author:

    Veerappan, RM and Malarvili T

    Title: Lipid profiles and marker enzymes in alcoholic hypertensive patients with/without diabetes
    Journal:JPR:BioMedRx:An International Journal
    Vol(issue):1 (April)
    Year:2013
    Page No: (418-421)
  • Experimental Methods Keywords

    Methodology:total cholesterol, LDL Cholesterol and VLDL Cholesterol, TG levels and TC/HDL ratio
    Research Materials:alcoholic hypertensive patients

Keywords

VLDL – very low density lipoprotein HDL-High density lipoprotein AST – Aspartanine transaminase ALT- Alanine transaminase.

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