Journal: Drug Invention Today

Article Id: JPRS-P col-00003179
Title: Gingival crevicular fluid level of interleukin 1 in chronic periodontitis with diabetes mellitus
Category: Pharmaceutics
Section: Review Article
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    The aim is to review the gingival crevicular fluid (GCF) level of interleukin 1 (IL-1) in chronic periodontitis with diabetes mellitus. Diabetes and periodontal illnesses show a bidirectional relationship focused on an improved provocative reaction that shows both locally and fundamentally. Periodontitis may occur in patients with and without Type 2 diabetes. GCF is an exudate that can be collected from the sulcus or periodontal pocket. Different pro-inflammatory cytokines are communicated in the GCF of diabetic patients with PD. It may be hypothesized that the GCF cytokine profile in patients with periodontitis with poorly controlled Type 2 diabetes may differ from the GCF cytokine profile in medically healthy individuals with periodontitis. IL-1β is a potent stimulator of bone resorption and has been implicated in the pathogenesis of periodontal destruction. From various studies, it was found that GCF IL-1 levels were elevated and also it was found to be a potential biomarker in patients with chronic periodontitis and diabetes mellitus.

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    Author(s) Name:

    S. Pooja, Sheeja Varghese

    Affiliation(s) Name:

    Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. Sheeja Varghes, Saveetha Dental College, Saveetha University, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

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    Author:

    S. Pooja, Sheeja Varghese

    Title:Gingival crevicular fluid level of interleukin 1 in chronic periodontitis with diabetes mellitus
    Journal:Drug Invention Today
    Vol(issue):12 (February)
    Year:2019
    Page No: (277-280)
  • Experimental Methods Keywords

    Methodology:chronic periodontitis
    Research Materials:Diabetes

Keywords

Biomarker Diabetes Gingival crevicular fluid Interleukin 1 Periodontal disease

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