Oral submucous fibrosis (OSMF) is a chronic, complex potentially malignant disorder. It is characterized by juxtaepithelial inflammatory reaction. It is characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. The etiology is multifactorial tobacco, areca nut chewing, consumption of chilies, genetics, and nutritional deficiency. There is a burning sensation followed by blisters, stomatitis, stiffness of tissues, and difficulty in mouth opening. This review attempts to give a comprehensive outline of the classification, clinical and histopathological features, etiology, pathogenesis, and treatment of OSMF.
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About the authors and Affiliations
Name
JPR Solutions
Author(s) Name:
Monisha Shankar1 , K. R. Don2 *
Affiliation(s) Name:
1 Graduate Student, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India,
2 Senior Lecturer, Department of Oral and Maxillofacial Pathology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India
*Corresponding author:K. R. Don, Department of Oral and Maxillofacial Pathology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, 162, PH Road, Chennai - 600 077, Tamil Nadu, India.