Journal: Drug Invention Today

Article Id: JPRS-P col-00003300
Title: Assessment of diabetic peripheral neuropathy in type 2 diabetes patients by Biothesiometer
Category: Pharmaceutics
Section: Research Article
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    Aim: The present study was aimed to assess the presence of diabetic neuropathy in type 2 diabetes patients. Objective: The objective of this study was to analyze the prevalence of diabetic neuropathy by detecting vibration perception threshold by an instrument called Biothesiometer. Materials and Methods: Our study conducted with 150 type 2 diabetes patients in outpatient diabetic center, after getting ethics permission from the institutional ethics committee. Demographic parameters were analyzed by Microsoft Excel. Patients were analyzed for the vibration perception threshold using Biothesiometer. The results were documented as Grades I (normal), II (mild), III (moderate), and IV (severe). Results: Our study consists of a total of 150 diabetes patients, male and female were found to be 54% and 46%. The mean age of patient was 54.85 and duration of diabetes was 10.05 years. VPT score Grade I (Normal) 68.67% was documented in our study. A total of Grades II, III, and IV were 15.33%, 8%, and 8%. Gender-wise categorization results from male (35.8%) and female (26.44%) were affected. Age-wise categorization, male patients (35.8%) were more affected than women (26.08%). A total of 19.14% of Grades II, III, and IV were found in the age group of <50 years and a total of 36.88% of mild, moderate, and severe were found in the age group of >50 years. Conclusion: The result of our study concluded that diabetic neuropathy increases with increase in age and duration of diabetes. Vibration perception threshold detection was useful method to identify patients affected from diabetic neuropathy.

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    Author(s) Name:

    P. Geetha1 , P. Shanmugasundaram2 *

    Affiliation(s) Name:

    1Research Scholar, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Chennai, Tamil Nadu, India,

    2 Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. P. Shanmugasundaram, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, Tamil Nadu, India.

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    Author:

    P. Geetha1 , P. Shanmugasundaram2 *

    Title:Assessment of diabetic peripheral neuropathy in type 2 diabetes patients by Biothesiometer
    Journal:Drug Invention Today
    Vol(issue):12 (March)
    Year:2019
    Page No: (541-544)
  • Experimental Methods Keywords

    Methodology:Biothesiometer
    Research Materials:Type 2 diabetes patients

Keywords

Biothesiometer Diabetic peripheral neuropathy Vibration perception threshold

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