Journal: Drug Invention Today
Title: Prevention of amoxicillin-induced post-extraction bleeding with tranexamic acid rinses in anticoagulated patients: A review literature
Category: Pharmaceutics
Section: Research Article
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Abstract
Background: Patients on oral anticoagulant therapy for a chronic period of time have greater tendency of postoperative bleeding and these patients cannot discontinue their oral anticoagulant abruptly to undergo dentoalveolar surgery therefore special care is to be taken to treat these patients. Cardiologist opinion is a must for these patients for us to carry out the surgery, PT-INR, bleeding time and clotting time values are to be reassured. Conclusion: Meticulous attention should be paid to while prescribing antibiotic medications in anticoagulated patients that may affect metabolism of warfarin. Since tranexamic acid has antifibrinolytic property, it remains as the most preferred drug over decades to prevent as well as treat hyperfibrinolysis and therefore it reduces mortality.
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About the authors and Affiliations
Author(s) Name: Vigneswaran T*, Chandhini Asokan
Affiliation(s) Name: Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, India
*Corresponding author: Dr. Vigneswaran, Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital, Velachery Main Road, Narayanapuram, Pallikaranai, Chennai - 600 077, Tamil Nadu, India.
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Author: Vigneswaran T*, Chandhini Asokan
Title: Prevention of amoxicillin-induced post-extraction bleeding with tranexamic acid rinses in anticoagulated patients: A review literature Journal: Drug Invention Today Vol(issue): 11 (April) Year: 2019 Page No: (933-934) -
Experimental Methods Keywords
Methodology: Prevention of amoxicillin-induced post-extraction bleeding Research Materials: Amoxicillin, Tranexamic acid rinse, Vitamin K
Keywords
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