Journal: Drug Invention Today

Article Id: JPRS-P col-00003380
Title: Comparison of antibacterial efficacy of essential oils with 2% chlorhexidine in reducing Enterococcus faecalis count
Category: Pharmaceutics
Section: Research Article
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    Introduction: The spread of drug-resistant pathogens is one of the most serious threats to successful treatment of microbial diseases. Down the ages, essential oils and other extracts of plants have evoked interest as sources of natural products. They have been screened for their potential uses as alternative remedies for the treatment of many infectious diseases. Methodology: Test microorganisms: Bacterial strain used was Enterococcus faecalis. The organism was isolated and maintained in nutrient agar slope at 4°C in the Department of Microbiology, Saveetha Dental College. The essential oils, lavender oil, sandalwood oil, peppermint oil, rosemary oil, clove oil, and cinnamon oil were used in the following concentrations – 25 μl, 50 μl, and 100 μl, respectively. Results: The antibacterial activity of the essential oils at different concentrations was screened by disk diffusion technique, and the zone of inhibition was measured in mm diameter. The results are given in the table. Peppermint oil was more effective against E. faecalis with a zone of inhibition of diameter 45 mm (at conc. of 100 μl), followed by rosemary oil and cinnamon oil with a zone of inhibition of diameter 35 mm (at conc. of 100 μl). Conclusion: Our observations confirm that peppermint oil might be considered as an effective antibacterial irrigation solution as it has a zone of inhibition of diameter 45 mm at conc. of 100 μl which is similar to the control chlorhexidine.

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    Author(s) Name:

    Nashwah Hinaz1 , R. V. Geetha2 *

    Affiliation(s) Name:

    1 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. V. Geetha, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600 077, Tamil Nadu, India.

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    Author:

    Nashwah Hinaz1 , R. V. Geetha2 *

    Title:Comparison of antibacterial efficacy of essential oils with 2% chlorhexidine in reducing Enterococcus faecalis count
    Journal:Drug Invention Today
    Vol(issue):11 (April)
    Year:2019
    Page No: (978-980)
  • Experimental Methods Keywords

    Methodology:antibacterial efficacy
    Research Materials:essential oils, Chlorhexidine

Keywords

Antibacterial Chlorhexidine Enterococcus faecalis Essential oils

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