Journal: Drug Invention Today

Article Id: JPRS-P col-00003396
Title: Evaluation of follicle-stimulating hormone and luteinizing hormone levels in breast cancer
Category: Pharmaceutics
Section: Research Article
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    Introduction: Breast cancer is one among the most pervasive cancer of women and has a major role in death rate in relation to cancer. Due to breast cancer, there is about 60% mortality in the developing countries. The current study aimed to establish the association of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) level in breast cancer. Materials and Methods: Patients were selected from those attending the outpatient department of Saveetha Dental College and Hospitals and divided into two groups as follows: Group I consists of normal healthy individuals and Group II consists of known breast cancer patients. Each group contains 30 participants. Individuals with the age group of 30–60 years, females with regular menstrual cycle were included in the study. Individuals with endocrine disorder or irregular menstrual cycle or polycystic ovary syndrome were excluded from this study. Results: All the data were analyzed using the SPSS package. Paired sample t-test analysis was done to find out significant differences between the two groups. All the tests were considered statistically significant at P < 0.05 level. Conclusion: The present study observed to have a higher serum FSH and LH levels in breast cancer patients. Hence, FSH and LH may have a role on breast cancer progression. Thus, advance studies are required to establish the accurate mechanism at the molecular level.

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    Author(s) Name:

    Thamarai Selvi, R. Gayatri Devi*, A. Jyothipriya

    Affiliation(s) Name:

    Department of Physiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. Gayatri Devi, Department of Physiology, Saveetha Dental College, Saveetha Institute of Technical and Medical Science, Saveetha University, 162, Poonamallee High Road, Chennai–600 077, Tamil Nadu, India.

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    Author:

    Thamarai Selvi, R. Gayatri Devi*, A. Jyothipriya

    Title:Evaluation of follicle-stimulating hormone and luteinizing hormone levels in breast cancer
    Journal:Drug Invention Today
    Vol(issue):12 (April)
    Year:2019
    Page No: (639-641)
  • Experimental Methods Keywords

    Methodology:Breast cancer , Follicle-stimulating hormone (FSH), Luteinizing hormone (LH)
    Research Materials:Patients

Keywords

Breast cancer Follicle-stimulating hormone (FSH) Luteinizing hormone (LH)

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