Journal: Drug Invention Today
Title: Characteristics and antioxidant activities of anthocyanin fraction in red dragon fruit peels (Hylocereus polyrhizus) extract
Category: Pharmaceutics
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Background: Dragon fruit has been reported for its high antiradical activities with the presence of phenolic compounds. Some significant characteristics of plant pigment are betacyanin, anthocyanins, and other flavonoids. This study aimed to determine the anthocyanin components, antioxidant activity, and Total phenolic content (TPC) of anthocyanin from the extract of red dragon fruit peels. Materials and Methods: The research was used methanol extraction, followed by other analyses, and thin-layer chromatography (TLC) to obtain the fractionated components. Anthocyanins were analyzed with a liquid chromatography-mass spectrometry (LC-MS) instrument to obtain cyanidin, malvidin, and delphinidin. Total phenolic content of anthocyanin was measured with Folin-Ciocaltau. Results: Antioxidant activity revealed 56.68% (crude extract), 36.91% (F3), and 36.24% (F9). This study used TLC followed by column chromatography for better separation of phenolics. Among the three samples, the highest radical scavenging activity demonstrated by lethal concentration50 was the crude extract, followed by F3 and F9. The LC-MS assay identified the single types of phenolic compounds such as cyaniding (31.63%), malvidin (7.37%), and delphinidin (7.53%). Conclusions: Red dragon fruit peel extract (Hylocereus polyrhizus) containing phytochemical compounds is an effective antioxidant from natural plant sources, with anticarcinogenic and anti-inflammation properties, and may help with other degenerative disorders.
-
Abstract Audio
No Audio file found
About the authors and Affiliations
Author(s) Name: Imam Prabowo1 *, Edi Priyo Utomo2 , Agung Nurfaizy2 , Aris Widodo3 , Edi Widjajanto4 , Puji Rahadju5
Affiliation(s) Name: 1 Department of Ear, Nose, and Throat Head and Neck Surgery, Faculty of Medicine, Sebelas Maret University, Surakarta 57126, Central Java, Indonesia,
2 Department of Chemistry, Faculty of Mathematic and Natural Sciences, Brawijaya University, Malang 65145, East Java, Indonesia,
3 Department of Pharmacy, Faculty of Medicine, University Brawijaya, Malang 65145, Indonesia,
4 Department of Clinical Pathology, Faculty of Medicine, Brawijaya University, Malang 65145, East Java, Indonesia,
5 Department of Ear, Nose, and Throat Head and Neck Surgery, Faculty of Medicine, Brawijaya University, Malang 65145, East Java, Indonesia
*Corresponding author: Imam Prabowo, Department of Ear, Nose, and Throat Head and Neck Surgery, Faculty of Medicine, Sebelas Maret University, Surakarta, Central Java, Indonesia.
-
View Article File in pdf format.
Article File
-
View Article Citation Here.
0 View More -
How to Cite my Article.
Author: Imam Prabowo1 *, Edi Priyo Utomo2 , Agung Nurfaizy2 , Aris Widodo3 , Edi Widjajanto4 , Puji Rahadju5
Title: Characteristics and antioxidant activities of anthocyanin fraction in red dragon fruit peels (Hylocereus polyrhizus) extract Journal: Drug Invention Today Vol(issue): 12 (April) Year: 2019 Page No: (670-678) -
Experimental Methods Keywords
Methodology: Antioxidant activities, Column chromatography, Fraction red dragon fruit (Hylocereus polyrhizus), Phenolic compound Research Materials: Red dragon fruit peels (Hylocereus polyrhizus) extract
Keywords
Our Services
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Awareness on soil pollution among school students
- Anti-oxidant activities of Biopolymeric Nanoparticles: Boon or Bane!
- Physiological changes in pregnancy
- Analysis of Amino Acids By Paper Chromatography
- Citric acid production from cane molasses using submerged fermentation by Aspergillus niger ATCC9142
- Awareness of effects of sleep deprivation among college students
- Formulation and evaluation of Aloe vera gels
- Plant natural products: Their pharmaceutical potential against disease and drug resistant microbial pathogens
- GC-MS study and phytochemical profiling of Mimosa pudica Linn.
- Hypovolemic shock - A review
- Effect of stress on academic performance of students in different streams
- Soxhlet Extraction of Neem seed (Azadirachta indica A. Juss) Using Hexane as a Solvent.
- Phytochemical standardization of the leaves of a medicinal plant Cipadessa baccifera Roth Miq.
- Biodegradable plastic production from corn starch
- Phytochemical Analysis of Cocos nucifera L
- Analgesic efficacy of lornoxicam compared to paracetamol in the treatment of post-extraction pain
- Studies on antifungal properties of Talisadi Churna on human pathogens
- A study of evaluation of body mass index and food pattern changes in patients undergoing orthodontic treatment
- Review On: Fast Dissolving Tablet
- Current Trends in Herbal Medicines
- In vivo and in silico studies with the latex of the milk weed- Calotropis procera (Ait) R.Br
- A Comparative study on Antioxidant, Proximate analysis, Antimicrobial activity and phytochemical analysis of Aloe vera and Cissus quadrangularis by GC-MS
- Synthesis and characterization new liquid crystals of Schiff base using microwave radiation
- Catheter Associated Urinary Tract Infection Susceptibility Pattern in Tertiary Care Hospital
- Evaluation of Anticonvulsant activity of methanolic extract of Artocarpus heterophyllus lam. (Moraceae) in mice.
- Antidepressant activity of ethanolic extract of leaves of Ocimum sanctum in mice
- Synthesis, and anti-cancer activity of some novel 3-(piperazin-1-yl)pyrazin-2-amine derivatives
- Role of Cactus grandiflorus in reversal of histological disruption and extent of infarction on isoproterenol-induced myocardial damage in wistar rats
- Application of nanotechnology for Ayurvedic drugs and formulations