Journal: Drug Invention Today

Article Id: JPRS-P col-00003409
Title: Relation analysis between triiodothyronine and thyroid-stimulating hormone in the serum of melasma patients
Category: Pharmaceutics
Section: Research Article
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    Background: Melasma is a condition of hypomelanosis related to triiodothyronine (T3) and thyroid-stimulating hormone (TSH). Methods: The analysis was conducted by taking those hormones from the serum of melasma patients. This cross- sectional study comprised 45 melasma patients aged 45–64 years. The measurements conducted were melisma area and severity index and the stress levels. Stress levels were determined by the Depression Anxiety Stress Scale questionnaire. Furthermore, T3 and TSH levels in patient serum were investigated. Results: About three-quarters of the patients (34 patients) showed a malar pattern of melasma. Furthermore, around half of the patients (23 patients) were diagnosed as experiencing normal stress, while 40% (18 patients) were diagnosed with moderate–severe stress levels. An average level of T3 serum was 1.15 ± 0.25 in stressed patient and 1.11 ± 0.29 in normal patient. An average level of TSH serum was 1.73 ± 1.25 in stressed patient and 1.72 ± 1.05 in normal patient. Conclusion: The levels of both T3 and TSH in stressed patients were considerably higher than in normal patients. However, this difference was not statistically significant.

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    Author(s) Name:

    Satya Wydya Yenny1 *, Yaslinda Yaunin2

    Affiliation(s) Name:

    1 Department of Dermatology-Venereology, Faculty of Medicine, Andalas University, West Sumatera, Indonesia,

    2 Department of Psychiatry, Faculty of Medicine, Andalas University, West Sumatera, Indonesia

    *Corresponding author: Satya Wydya Yenny, Department of Dermatology-Venereology, Faculty of Medicine, Andalas University, West Sumatera, Indonesia.

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    Author:

    Satya Wydya Yenny1 *, Yaslinda Yaunin2

    Title:Relation analysis between triiodothyronine and thyroid-stimulating hormone in the serum of melasma patients
    Journal:Drug Invention Today
    Vol(issue):12 (April)
    Year:2019
    Page No: (711-714)
  • Experimental Methods Keywords

    Methodology:Stress, Thyroid-stimulating hormone,Stress levels
    Research Materials:Melasma patients

Keywords

Melasma Stress Thyroid-stimulating hormone Triiodothyronine

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