Journal: Drug Invention Today

Article Id: JPRS-P col-00003436
Title: Assessment of salivary toxic thiocyanate level in smokers with or without leukoplakia
Category: Pharmaceutics
Section: Research Article
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    Background: Leukoplakia which is also a form of cancer is now becoming deadly if not treated properly. This is more manifested in smokers, or in a way, we can say that smoking is one causative reason for leukoplakia. Objective: The objective of this study was to determine the level of salivary thiocyanate (SCN) with or without leukoplakia. Materials and Methods: The present study was conducted on subjects who are habitual to smoking with or without leukoplakia reporting to the Department of Oral Medicine and Radiology at Saveetha Dental College and Hospitals, SIMATS, Chennai, India. A sample size of 20 was taken for the study and biochemical tests were done and the results obtained were statistically analyzed. Results: The level of SCN is observed higher among smokers with leukoplakia than smokers without leukoplakia. Conclusion: This study shows that the patients who have high levels of cigarette intake induced leukoplakia have higher the chances of getting oral carcinoma and, hence, measuring SCN levels as non-invasive method to identify a biomarker for leukoplakia.

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    Author(s) Name:

    V. Kayal 1 , V. Vishnu Priya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1 , Adithya R. Pillai 2 , J. Selvaraj1 *

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. J. Selvaraj, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    V. Kayal 1 , V. Vishnu Priya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1 , Adithya R. Pillai 2 , J. Selvaraj1 *

    Title:Assessment of salivary toxic thiocyanate level in smokers with or without leukoplakia
    Journal:Drug Invention Today
    Vol(issue):12 (April)
    Year:2019
    Page No: (809-812)
  • Experimental Methods Keywords

    Methodology:Determining the Levels of Thiocyanate in Saliva
    Research Materials:smokers with or without leukoplakia

Keywords

Leukoplakia Smokers Salivary thiocyanate

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