Journal: Drug Invention Today
Title: An in vitro antioxidant and antibacterial activity of Siddha polyherbal preparations on selected human pathogenic microorganisms
Category: Pharmaceutics
Section: Research Article
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Abstract
Background: Key concept of Siddha is harmony with nature and the universe. The Siddha plays a major role in curing many diseases. It does not have any side effects, but its curing time is prolonged. The Siddha polyherbal used in this study is a combination of four plants such as Asparagus racemosus, Syzygium aromaticum, Emblica officinalis, and Tinospora cordifolia. These herbs are found in India, Indonesia, Nepal, Sri Lanka, The Himalayas, and Africa. These herbs cure many of the diseases. Objective: The objective was to study the in vitro antioxidant and antibacterial activity of Siddha polyherbal on selected human pathogens. Materials and Methods: To check the antioxidants and antimicrobial properties of Siddha polyherbal drugs, the polyherbal powder was extracted with 45% ethanol by Soxhlet apparatus at 45°C. After 24 h of incubation period, the plates were observed and the inhibition zone was recorded. Results: The investigation of antibacterial activity of Siddha polyherbal extracts against Gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis and Gram-negative bacteria such as Pseudomonas aeruginosa was done by agar well diffusion method. The inhibition zone is maximum in larger area in all the three bacteria. There is no control used in this study. The Siddha medicines show the slow effect, but there are no side effects. Mean zone of the inhibition of different concentrations is measured. Conclusion: Based on the results recorded in the present findings, it is concluded that Siddha polyherbal preparation has a potential antimicrobial agent on human oral pathogenic microorganisms, and hence, the herbal drug may serve as one of the potential antimicrobial agents.
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Author(s) Name: S. Balamithra1 , V. Vishnu Priya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1 , J. Selvaraj1 *
Affiliation(s) Name: 1 Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,
2 Department of Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, India.
*Corresponding author: Dr. J. Selvaraj, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai–600 077, Tamil Nadu, India
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Author: S. Balamithra1 , V. Vishnu Priya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1 , J. Selvaraj1 *
Title: An in vitro antioxidant and antibacterial activity of Siddha polyherbal preparations on selected human pathogenic microorganisms Journal: Drug Invention Today Vol(issue): 12 (April) Year: 2019 Page No: (820-822) -
Experimental Methods Keywords
Methodology: Antioxidant and antibacterial activity Research Materials: Siddha polyherbal drug
Keywords
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