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Abstract

Because of the evolving resistance of microorganisms to existing antibiotics, there is an increasing need for new antibiotics. Since seaweeds offer particularly rich source of bioactive molecules, the present study was carried out to investigate the antimicrobial potentiality of the marine algae, two species of brown algae namely Sargassum ilicifolium, Padina tetrastromatica and one red algae Gracilaria corticata collected from different coastal regions. For microbiological testing of the seaweed extracts, agar well diffusion method was used. The zone of inhibition was measured for all the Different crude algal extracts (Chloroform, ethanol, methanol and water) against six strains of Gram positive, Gram negative bacterial and Fungal organisms that cause diseases and disorders in man, animals and plants.Crude extracts revealed a wide range of antimicrobial activity against tested pathogens. Seaweed extracts in different solvents exhibited different antimicrobial activities. In case of Sargassum ilicifolium, Padina tetrastromatica, of the various solvents used for seaweed extractions, maximum inhibition was noticed with ethanol extracts and minimum with chloroform crude extracts while in case of Gracilaria corticata, maximum inhibition was noticed with methanol and minimum with chloroform extracts. However, no specific solvent exhibited activity against all the test organisms effectively. Further bacterial strains were more sensitive to the extracts when compared to the fungal organisms. The overall antimicrobial activity assessed from the above results indicates the presence of active constituents in the extractions of seaweeds which can be exploited for the production of lead molecules which are of use in pharmaceutical industry.

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	JPR Solutions

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