Logo

Abstract

Aim: This study aims to compare the effectiveness of tranexamic acid and hemocoagulase (Botroclot) bleeding management in dental extraction patients. Background: Tranexamic acid is an antifibrinolytic agent that blocks lysine-binding sites on plasminogen, thereby reducing the local degradation of fibrin by plasmin. It works to stabilize and to inhibit the degradation of existing clots, and it is widely used to limit bleeding in clinical practice. Hemocoagulase reduces the bleeding time and promotes wound healing by promoting the growth of capillaries in wound space. Methodology: A total of 10 periodontally compromised patients requiring bilateral extraction were selected. Post-extraction, bleeding cessation was estimated by placing tranexamic acid soaked gauze on the extraction socket. After a week, the patients were recalled for extraction on contralateral side, bleeding cessation was estimated by placing hemocoagulase soaked gauze on the extraction socket. The bleeding time was noted and bleeding scores were estimated in both hemostatic agent patients. Results: Bleeding from extraction sockets was successfully ceased by compression of socket with the topical hemostatic agents soaked in gauze. There was no significant difference between tranexamic acid and hemocoagulase (P = 0.7) observed in bleeding management post-dental extraction. Conclusion: There is no significant difference between tranexamic acid and hemocoagulase in bleeding management; hence, both hemostatic agents are equally effective in the management of bleeding post-extraction.

Abstract Audio

No Audio file found

About the authors and Affiliations

	Name
	JPR Solutions

View Article File in pdf format.

Article File

View Article Citation Here.

How to Cite my Article.

Experimental Methods Keywords