Journal: Drug Invention Today

Article Id: JPRS-P col-00003692
Title: Evaluation of the effect of Glycyrrhiza glabra as root canal disinfectant - An in vitro study
Category: Pharmaceutics
Section: Research Article
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    Aim: The aim of the study was to evaluate the effect of Glycyrrhiza glabra as root canal disinfectant. Background: Liquorice is the root of G. glabra from which a sweet flavor can be extracted. A number of pharmaceutical effects of liquorice are known anti-inflammatory, antiviral, and anticarcinogenic. Glycyrrhizin, a triterpenoid compound, accounts for the sweet taste of liquorice root. Liquorice has also shown greater biocompatibility with fibroblasts cells compared to calcium hydroxide, which was severely toxic to the cells. Materials and Methods: In vitro studies were conducted using freshly extracted single-rooted premolars. Using a Gates Glidden drill, root canal was enlarged. Enterococcus faecalis was used as the culture suspension against which the activity of the extract was tested. Conclusion: Liquorice (G. glabra) shows effective bactericidal activity against E. faecalis and can be used as an effective root canal disinfectant.

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    Author(s) Name:

    Gokul Gunasekaran1 , R. V. Geetha1 *, Lakshmi Thangavelu2

    Affiliation(s) Name:

    1 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. V. Geetha, Department of Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, No. 162, Poonamallee High Road, Chennai – 600 077, Tamil Nadu, India

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    Author:

    Gokul Gunasekaran1 , R. V. Geetha1 *, Lakshmi Thangavelu2

    Title:Evaluation of the effect of Glycyrrhiza glabra as root canal disinfectant - An in vitro study
    Journal:Drug Invention Today
    Vol(issue):12 (June)
    Year:2019
    Page No: (1323-1325)
  • Experimental Methods Keywords

    Methodology: Bactericidal, Root canal
    Research Materials:Disinfectant, Glycyrrhiza

Keywords

Bactericidal Disinfectant Enterococcus faecalis Glycyrrhiza Root canal

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