Journal: Drug Invention Today

Article Id: JPRS-P col-00003699
Title: Comparative study on antibacterial effects of ethanolic leaf extracts of guava in variants of red and white pulp (Psidium guajava) against sensitive and chloramphenicol-resistant Staphylococcus aur
Category: Pharmaceutics
Section: Research Article
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    Aim: This study aims to compare the antibacterial potential of red and white pulp guava (Psidium guajava) leaf extracts against sensitive and chloramphenicol-resistant Staphylococcus aureus. Materials and Methods: The antibacterial effect of each guava leaf extract was evaluated against sensitive and chloramphenicol-resistant S. aureus using an agar well diffusion method. The minimum inhibitory concentration (MIC) value of the potential extract was determined using the macrodilution method. Results and Discussion: The antibacterial study showed that the red and white guava leaf extracts were potential to inhibit the sensitive S. aureus, but not to the resistant one. According to the data of inhibitory diameters against sensitive S. aureus, the ethanol extracts of the red guava leaves showed stronger inhibitory activity than the white guava. The MIC value of red guava leaf extracts was in the range of 0.195–0.391% w/v. Conclusion: The leaf extract of red pulp guava was found to be a potent antibacterial candidate for a natural anti-staphylococcal agent.

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    Author(s) Name:

    Sri Agung Fitri Kusuma1 *, Niko Tanzillafitsi 2 , Mia Resmiati 2

    Affiliation(s) Name:

    1 Department of Biology Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java 45363, Indonesia,

    2 Departement of Pharmacy, Faculty of Mathematics and Natural Sciences, Al-Ghifari University, Bandung, West Java, Indonesia

    *Corresponding author: Sri Agung Fitri Kusuma, Department of Biology Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java 45363, Indonesia.

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    Author:

    Sri Agung Fitri Kusuma1 *, Niko Tanzillafitsi 2 , Mia Resmiati 2

    Title:Comparative study on antibacterial effects of ethanolic leaf extracts of guava in variants of red and white pulp (Psidium guajava) against sensitive and chloramphenicol-resistant Staphylococcus aur
    Journal:Drug Invention Today
    Vol(issue):11 (July)
    Year:2019
    Page No: (1519-1522)
  • Experimental Methods Keywords

    Methodology:Antibacterial effects
    Research Materials:Leaf extract, Psidium guajava, Red guava

Keywords

Chloramphenicol Leaf extract Psidium guajava Red guava Staphylococcus aureus White guava

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