Journal: Drug Invention Today

Article Id: JPRS-P col-00003738
Title: Anti-inflammatory activity of heartwood of Acacia catechu Willd.: Preliminary analysis
Category: Pharmaceutics
Section: Research Article
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    Aim: The aim of this study was done to assess the anti-inflammatory property of heartwood of Acacia catechu Willd. through protein denaturation test. Materials and Methods: The test solution, standard solution, product control, and test control solutions were incubated at 37°C for 20 min and heated for 3 min and all the solutions were analyzed by spectrophotometer to obtain their optical density and the inhibition percentage was called using a standard formula for varying concentration of the A. catechu Willd. and the results were tabulated and compared with the inhibition percentage of diclofenac sodium which is a standard anti-inflammatory drug. Results: Heartwood of A. catechu Willd. has shown mild anti-inflammatory activity when compared to the diclofenac sodium which is a standard anti-inflammatory activity. There is also an increase in the anti- inflammatory activity with increase in concentration of the test substrate. Conclusion: It is a promising alternative for the management of candidates with autoimmune inflammatory disorders such as rheumatoid arthritis. The use of these extracts will be greatly beneficial in inhibition of protein denaturation which causes the inflammation and, hence, can be used for the treatment of arthritis.

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    Author(s) Name:

    Jembulingam Sabarathinam, Lakshmi Thangavelu*

    Affiliation(s) Name:

    Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Lakshmi Thangavelu, Department of Pharmacology, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

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    Author:

    Jembulingam Sabarathinam, Lakshmi Thangavelu*

    Title:Anti-inflammatory activity of heartwood of Acacia catechu Willd.: Preliminary analysis
    Journal:Drug Invention Today
    Vol(issue):11 (July)
    Year:2019
    Page No: (1669-1671)
  • Experimental Methods Keywords

    Methodology:Anti-inflammatory, Herbal, Inflammatory disorders, Protein denaturation
    Research Materials: Acacia catechu Willd.

Keywords

Anti-inflammatory Herbal Inflammatory disorders Protein denaturation

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