Article Id:JPRS-P col-00003858 Title:In vitro anti-inflammatory activity of Plumeria acuminata using membrane stabilization assay Category:Pharmaceutics Section:Research Article
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Introduction: Plumeria acuminata this is commonly called as perungalli in Tamil language belongs to the family of Apocynaceae that can be widely found in India mostly in southern parts. The leaves of the plant are enriched with the milky juice that contains the property of anti-inflammatory property. The decoction of leaves is applied for cracks and eruption of the soles of the feet. P. acuminata is known as good terminator for the reaction due to inflammation. Materials and Methods:The leaves of P. acuminata are collected and the plant extract was taken; then, we check for anti-inflammatory using membrane stabilization assay. The steps involved are the preparation of red blood cell suspension then using heat-induced hemolysis assay. We can find the anti-inflammatory property. Results:Small dose cures the inflammation when the concentration increases the side effects also increases. Hence, it is good to use in small concentration. Conclusion: The leaves of P. acuminata contain anti-inflammation activity. Thus, it can be used as future medicine in small quantities.
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JPR Solutions
Author(s) Name:
K. Thirumagal, R.V. Geetha*
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Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
*Corresponding author:R.V. Geetha, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.