Journal: Drug Invention Today
Title: Cytotoxic potential of cow ghee on the human epidermoid cell lines
Category: Pharmaceutics
Section: Research Article
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Abstract
Aim: The main objective of this study is to analyze the cytotoxic effect of cows ghee on the oral cancer cell lines (KB cell lines). Materials and Methods: KB cell line: KB cell line was procured from NCCs, Pune, and maintained in Dulbecco’s Modified Eagle’s Medium. Test drug: Cow ghee extract was used. Cytotoxic assay: Cytotoxicity of the extract was analyzed by 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and compared with standard drug cisplatin. Results and Discussion: Results were expressed as mean ± SD. Statistical significance was determined by one-way analysis of variance and post hoc least significant difference test. P < 0.05 was considered statistically significant. From the study, it is evident that cows ghee possessed cytotoxic potential against KB cell line in dose-dependent manner as compared to the standard drug cisplatin
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About the authors and Affiliations
Author(s) Name: S. Jitesh, R. Gayathri*, V. Vishnu Priya
Affiliation(s) Name: Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
*Corresponding author: R. Gayathri, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 160, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.
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Author: S. Jitesh, R. Gayathri*, V. Vishnu Priya
Title: Cytotoxic potential of cow ghee on the human epidermoid cell lines Journal: Drug Invention Today Vol(issue): 12 (August ) Year: 2019 Page No: (1704-1706) -
Experimental Methods Keywords
Methodology: Cytotoxic potential, Human epidermoid cell lines Research Materials: Cow ghee
Keywords
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