Journal: Drug Invention Today

Article Id: JPRS-P col-00003963
Title: Study on prescription pattern of antihypertensive drugs among acute coronary syndrome patients in South Indian population
Category: Pharmaceutics
Section: Research Article
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    Background: Hypertension or high blood pressure is a condition, in which the force of the blood against the artery walls is too high. The increasing prevalence of the condition is blamed on lifestyle and dietary factors such as physical inactivity, alcohol and tobacco use, and a diet high in sodium. Hypertension can be primary and secondary. Primary hypertension results from a complex interaction of genes and environmental factors. Secondary hypertension results from identifiable cause. Long-term prevalence of this can lead to major health risks. Aim: The present study evaluates the drug utilization pattern of antihypertensive drugs in acute coronary syndrome (ACS) patients among South Indian population. Materials and Methods: This prospective observational study was conducted for a period of 1 month (December 2016) based on in and outpatient medical records of patients admitted in Saveetha Medical College and Hospital in Chennai. Fifty patients were selected based on inclusion and exclusion criteria. Only patients with ACS and hypertension were included in the study. Non-hypertensive ACS patients and hypertensive patients with no signs of ACS were excluded from the study. The prescription forms were analyzed for various parameters such as gender of the patient, type of antihypertensive drugs used, type of therapy (monotherapy or two drug combination therapies), and other diseases associated with hypertension. Results: About 53% of the patients were prescribed amlodipine, 22% of the patients were described atenolol, 20% of the patients were prescribed enalapril, and 5% of the patients were prescribed diltiazem. Conclusion: Monotherapy was the most commonly used mode of treatment according to the current study. However, it does not indicate that monotherapy is better or more efficient than the other since the treatment of choice also depends on the severity of the condition and the patient’s history. If the patient response to monotherapy is less, then combination therapy is used for better prognosis.

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    Author(s) Name:

    V. P. Pathmashri , V. Vikranth , Dhanraj Ganapathy *

    Affiliation(s) Name:

    1 Department of  Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of General Medicine, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dhanraj Ganapathy, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

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    Author:

    V. P. Pathmashri , V. Vikranth , Dhanraj Ganapathy *

    Title:Study on prescription pattern of antihypertensive drugs among acute coronary syndrome patients in South Indian population
    Journal:Drug Invention Today
    Vol(issue):11 (September )
    Year:2019
    Page No: (2073-2076)
  • Experimental Methods Keywords

    Methodology:Acute coronary syndrome,Hypertension, Prescription pattern
    Research Materials:Antihypertensive drugs

Keywords

Acute coronary syndrome Antihypertensive drugs Hypertension Prescription pattern

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