Journal: Drug Invention Today

Article Id: JPRS-P col-00003970
Title: Structural annotation of hypothetical proteins of Streptococcus mutans
Category: Pharmaceutics
Section: Research Article
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    Introduction: Streptococcus mutans is one of the serious pathogens, facultative Gram-positive, anaerobic cocci predominantly found in the human oral cavity known to be involved in promoting tooth decay. Although the genome of this bacterium is already sequenced, there still remain proteins for which neither the function nor the structures are known yet. Therefore, in this study, we will be performing structural annotation of the hypothetical proteins present in S. mutans to find proteins that are similar in fold for further understanding. Materials and Methods: The FASTA sequence of the selected hypothetical protein of S. mutans was subjected to structural annotation using the online server HHpred. Results and Conclusion: It was found that the hypothetical proteins which were selected had glucosyltransferase function and structural annotation supported the finding.

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    Author(s) Name:

    M. Aparnaa, V. Vishnu Priya*, R. Gayathri

    Affiliation(s) Name:

    Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai- 600 077, Tamil Nadu, India.

    *Corresponding author: V. Vishnu Priya, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    M. Aparnaa, V. Vishnu Priya*, R. Gayathri

    Title:Structural annotation of hypothetical proteins of Streptococcus mutans
    Journal:Drug Invention Today
    Vol(issue):11 (September )
    Year:2019
    Page No: (2108-2112)
  • Experimental Methods Keywords

    Methodology:Structural annotation
    Research Materials:Streptococcus mutans

Keywords

Glucosyltransferase HHpred Hypothetical protein Streptococcus mutans Structural annotation

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