Journal: Drug Invention Today

Article Id: JPRS-P col-00003992
Title: Anti-alopecia activity of waste cacao (Theobroma cacao L.) peels
Category: Pharmaceutics
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Objective: Hair loss (alopecia) is the most common hair problem. The objective of this study was to determine the activity of growth stimulant activity of cacao (Theobroma cacao L.) fruit peels. Materials and Methods: The cacao peel extract was extracted with ethanol 96% solvent and fractionated with water. n-hexane and ethyl acetate solvents and then tested for hair growth stimulant activity of extracts and waste cacao peels fraction with modified Tanaka et al. method. In this test, the concentration of ethanol extract of cacao fruit peel was diluted to 5%, 10%, 15%, 20%, and 25% which were tested in test animals, namely, rabbits. Results and Discussion: The results showed that the test results showed that the ethanol extract of cacao fruit peel effluent had a hair growth stimulating activity starting at a concentration of 15%. In testing the fraction of cacao fruit peel fraction, it was found that the n-hexane fraction had the best activity compared to the other fractions and positive controls (minoxidil 2%). All data obtained in the study were analyzed statistically. Conclusion: Waste cacao peels ethanol extract had a growth stimulant activity at a concentration above 15% with the n-hexane fraction had the best activity.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Resmi Mustarichie*, Aliya Nur Hasanah

    Affiliation(s) Name:

    Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, 45363, Indonesia

    *Corresponding author: Resmi Mustarichie, Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, 45363, Indonesia.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Resmi Mustarichie*, Aliya Nur Hasanah

    Title:Anti-alopecia activity of waste cacao (Theobroma cacao L.) peels
    Journal:Drug Invention Today
    Vol(issue):11 (September )
    Year:2019
    Page No: (2194-2199)
  • Experimental Methods Keywords

    Methodology:Anti-alopecia, Cacao fruit peel waste, Extraction, Hair loss
    Research Materials:Theobroma cacao

Keywords

Anti-alopecia Cacao fruit peel waste Extraction Hair loss Theobroma cacao

Our Services

Most Downloaded List