Journal: Journal of Pharmacy Research

Article Id: JPRS-PC-0000404
Title: Ethyl caffeate ether derivatives as future potential drug
Category: Pharmaceutical Chemistry
Section: Research Article
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    Ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate were treated with various alkyl halides in presence of K2CO3 and acetone to obtain their ether derivatives. Further methyl and ethyl ethers were also obtained using DMS and DES respectively. The structure of these compounds were confirmed by IR, NMR and Mass Spectroscopy. All the compounds give satisfactory elemental analysis. Few of them showing promising Antibacterial activity.

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    Author(s) Name:

    Vijay D. Gangana*, Lijy Jazlya, Chaitaly T. Chakrabortya, Deepak S. Bhatiaa,
    Aparna S. Deshmukha, Satish M. Bhalekarb, Sharad S. Sankhec and Gurunath Pujarid

    Affiliation(s) Name:

    aDepartment of Chemistry, Thakur College of Science & Commerce, Thakur Village, Kandivali ( E ), Mumbai- 400 101.
    bDepartment of Chemistry, S.I.W.S. College, Wadala, Mumbai- 400 031,India.
    cDepartment of Chemistry, Patkar college of Arts, Commerce and Science, Goregaon (W), Mumbai 400062,India
    dDepartment of Chemistry, Shivajirao Jondhale College of Engineering, Dombivali (E), Mumbai,India

    *Corresponding author.
    Dr.Vijay D. Gangan
    Department of Chemistry,
    Thakur College of Science & Commerce,
    Thakur Village, Kandivali ( E ),
    Mumbai- 400 101,India

    Received on:21-04-2014; Revised on: 17-05-2014; Accepted on:11-06-2014

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    Author:

    Vijay D. Gangana*, Lijy Jazlya, Chaitaly T. Chakrabortya, Deepak S. Bhatiaa,
    Aparna S. Deshmukha, Satish M. Bhalekarb, Sharad S. Sankhec and Gurunath Pujarid

    Title:Ethyl caffeate ether derivatives as future potential drug
    Journal:Journal of Pharmacy Research
    Vol(issue):8 (June)
    Year:2014
    Page No: (818-821)
  • Experimental Methods Keywords

    Methodology:Antibacterial Activity
    Research Materials: Caffeic acid,

Keywords

Caffeic acid CAPE NF-κB antibacterial fungicidal 1HNMR TOF MS elemental analysis.

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