Journal: Drug Invention Today

Article Id: JPRS-P col-00004055
Title: In vitro effects of hyaluronic acid on human gingival fibroblast cells
Category: Pharmaceutics
Section: Research Article
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  • Abstract

    Introduction: Hyaluronic acid is a glucosaminoglycan that is naturally present in human body. It’s highest concentration is in eye and joints. Interleukin are group of cytokines expressed by WBC. Materials and Methods: Human gingival fibroblast cells was produced and maintained in DMEM medium. To this HA was added to induce interleukin secretion. Interleukin causes dose dependent increase upon incorporation of HA. Result and Conclusion: IL 6 and 8 secretion was maximum in HA untreated HGF cells. There was a contaminate decrease in interleukin secretion observed with increase in concentration of HA as compared to positive control mitomycin C.

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    Author(s) Name:

    Sri Kala Priyadharshini, V. Vishnu Priya*, R. Gayathri

    Affiliation(s) Name:

    Department of  Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. V. Vishnu Priya, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Sri Kala Priyadharshini, V. Vishnu Priya*, R. Gayathri

    Title:In vitro effects of hyaluronic acid on human gingival fibroblast cells
    Journal:Drug Invention Today
    Vol(issue):12 (September )
    Year:2019
    Page No: (1929-1931)
  • Experimental Methods Keywords

    Methodology:Fibroblast, Interleukin,
    Research Materials:Hyaluronic acid

Keywords

Fibroblast Hyaluronic acid Interleukin

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