Journal: Drug Invention Today

Article Id: JPRS-P col-00004113
Title: Anti-inflammatory activity of zinc oxide nanoparticles prepared using amla fruits
Category: Pharmaceutics
Section: Research Article
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    Aim: Anti-inflammatory activity of zinc oxide (ZnO) nanoparticles prepared using amla fruit. Objective: Preparation of ZnO nanoparticles using amla fruit extract and its anti inflammatory activity. Materials and Methods: Collection and preparation of amla fruit extract, synthesis of ZnO nanoparticles using amla fruit extract, collection of NPs using centrifugation, anti- inflammatory activity of ZnO nanoparticle using ultraviolet-visible spectroscopy, and inhibition of albumin denaturation assay were used. Results: Aspirin, diclofenac, and ibuprofen are the most commonly used drugs for the inflammation which belongs to nonsteroidal anti-inflammatory group of drug. These drugs result in adverse side effects and damage the human biological system such as liver and gastrointestinal tract and may also cardiovascular system. According to the research, ZnO particles produced from amla fruit showed the anti-inflammatory activity and thus can be considered as a potential candidate as an anti-inflammatory agent, thus reducing the major health problems. Conclusion: The ZnO nanoparticles were synthesized from the amla fruit. All these data with results show that ZnO nanoparticle produced from amla fruit potent anti- inflammatory property. The present study shows that ZnO nanoparticle can be used for various medicinal purposes. Further investigations are required for the development of new classes of analgesics and anti-inflammatory drugs from amla fruit.

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    Author(s) Name:

    M. Rangeela, S. Rajeshkumar*, T. Lakshmi, Anitha Roy

    Affiliation(s) Name:

    Department of Pharmacology, Nanobiomedicine Lab, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. S. Rajeshkumar, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India

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    Author:

    M. Rangeela, S. Rajeshkumar*, T. Lakshmi, Anitha Roy

    Title:Anti-inflammatory activity of zinc oxide nanoparticles prepared using amla fruits
    Journal:Drug Invention Today
    Vol(issue):11 (October )
    Year:2019
    Page No: (2358-2361)
  • Experimental Methods Keywords

    Methodology:Anti-inflammatory, Zinc oxide nanoparticles
    Research Materials:Amla fruits

Keywords

Amla fruits Anti-inflammatory Zinc oxide nanoparticles

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