Journal: Drug Invention Today
Title: Dynamics of drug sustainability Mycobacterium tuberculosis in the Belgorod region for the period of 2008–2017
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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Abstract
Aim of the study: to assess and compare the structure and dynamics of Mycobacterium tuberculosis drug resistance to anti-tuberculosis drugs, including multiple and broad, in the Belgorod region in newly diagnosed patients and patients with relapses of tuberculosis. Methodology: the article analyzed the structure and dynamics of drug resistance of Mycobacterium tuberculosis to the main and reserve anti-tuberculosis drugs for the years 2008-2017 in the Belgorod region. The authors used data from statistical accounting forms 07-TB and the centralized bacteriological laboratory. For the ten-year period 2008 - 2017 in the Belgorod region, against the background of a happy tuberculosis epidemiological situation, a decrease in morbidity and mortality, there has been a general increase in the resistance of the pathogen to anti-tuberculosis drugs. An alarming tendency to an increase in the wide drug resistance of Mycobacterium tuberculosis strains is registered, which is an extremely unfavourable sign, significantly complicates the appointment of adequate therapy to patients and reduces the effectiveness of treatment. Conclusion: all of the above emphasizes the importance of monitoring the drug resistance of Mycobacterium tuberculosis, which is an integral part of controlling the spread of this infectious disease. It is necessary to continue this work, which will make it possible to predict the risk of spreading drug-resistant tuberculosis and differentiate the approach to anti-epidemic measures at the regional level.
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About the authors and Affiliations
Author(s) Name: Oleg А. Zemlyanski 1 *, Еlena B. Turina1,2 , Еlena V. Kaliuzhnaya1 , Alina M. Bronnikova1
Affiliation(s) Name: 1 Department of Microbiology, Belgorod State University, Belgorod, 308015, Russia,
2Tuberculosis Dispensary, 294, Volchanskaya Street., Belgorod, Russia
*Corresponding author: Oleg А. Zemlyanski, Department of Microbiology, Belgorod State University, 85 Pobedy Street, Belgorod, 308015, Russia.
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Author: Oleg А. Zemlyanski 1 *, Еlena B. Turina1,2 , Еlena V. Kaliuzhnaya1 , Alina M. Bronnikova1
Title: Dynamics of drug sustainability Mycobacterium tuberculosis in the Belgorod region for the period of 2008–2017 Journal: Drug Invention Today Vol(issue): 11 (October ) Year: 2019 Page No: (2415-2418) -
Experimental Methods Keywords
Methodology: Anti-epidemic measures, Research Materials: Antituberculosis drugs
Keywords
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