Journal: Drug Invention Today

Article Id: JPRS-MSNS-00004125
Title: Dynamics of drug sustainability Mycobacterium tuberculosis in the Belgorod region for the period of 2008–2017
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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    Aim of the study: to assess and compare the structure and dynamics of Mycobacterium tuberculosis drug resistance to anti-tuberculosis drugs, including multiple and broad, in the Belgorod region in newly diagnosed patients and patients with relapses of tuberculosis. Methodology: the article analyzed the structure and dynamics of drug resistance of Mycobacterium tuberculosis to the main and reserve anti-tuberculosis drugs for the years 2008-2017 in the Belgorod region. The authors used data from statistical accounting forms 07-TB and the centralized bacteriological laboratory. For the ten-year period 2008 - 2017 in the Belgorod region, against the background of a happy tuberculosis epidemiological situation, a decrease in morbidity and mortality, there has been a general increase in the resistance of the pathogen to anti-tuberculosis drugs. An alarming tendency to an increase in the wide drug resistance of Mycobacterium tuberculosis strains is registered, which is an extremely unfavourable sign, significantly complicates the appointment of adequate therapy to patients and reduces the effectiveness of treatment. Conclusion: all of the above emphasizes the importance of monitoring the drug resistance of Mycobacterium tuberculosis, which is an integral part of controlling the spread of this infectious disease. It is necessary to continue this work, which will make it possible to predict the risk of spreading drug-resistant tuberculosis and differentiate the approach to anti-epidemic measures at the regional level.

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    Author(s) Name:

    Oleg А. Zemlyanski 1 *, Еlena B. Turina1,2 , Еlena V. Kaliuzhnaya1 , Alina M. Bronnikova1

    Affiliation(s) Name:

    1 Department of  Microbiology, Belgorod State University, Belgorod, 308015, Russia,

    2Tuberculosis Dispensary, 294, Volchanskaya Street., Belgorod, Russia

    *Corresponding author: Oleg А. Zemlyanski, Department of Microbiology, Belgorod State University, 85 Pobedy Street, Belgorod, 308015, Russia.

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    Author:

    Oleg А. Zemlyanski 1 *, Еlena B. Turina1,2 , Еlena V. Kaliuzhnaya1 , Alina M. Bronnikova1

    Title:Dynamics of drug sustainability Mycobacterium tuberculosis in the Belgorod region for the period of 2008–2017
    Journal:Drug Invention Today
    Vol(issue):11 (October )
    Year:2019
    Page No: (2415-2418)
  • Experimental Methods Keywords

    Methodology:Anti-epidemic measures,
    Research Materials:Antituberculosis drugs

Keywords

Anti-epidemic measures Antituberculosis drugs Drug resistance Mycobacterium tuberculosis strains

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