Journal: Drug Invention Today

Article Id: JPRS-P col-00004129
Title: The effect of Nigella sativa and other plants on bacteria isolated from diabetic foot ulcers
Category: Pharmaceutics
Section: Research Article
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    Background: Diabetes mellitus is a chronic lifelong disorder distinguishes oneself by chronic hyperglycemia and caused damage of organs. Bad control of diabetes leads to skin infections and non-healing foot ulcers which common in clinical practice. The access to the hospital and mutilation will increase and conversely result in long-term economic, physical, social, and mental disability to the patient. Methodology: This study is designed to identified bacteria from diabetic foot ulcer (DFU) patients by tissue specimen and investigates the sensitivity of these bacteria to Nigella sativa (NS) oil, other essential oils, and compounds. Results: Staphylococcus epidermidis 50% was recorded the highest occurrence in patients followed by Klebsiella pneumoniae 20%, Staphylococcus aureus, and Escherichia coli 13.3%. Pseudomonas aeruginosa 3.3% was recorded as the lowest occurrence in patients. Polymicrobial growth cultures were present in 6 (100%) of patients and appeared as S. aureus with E. coli and K. pneumoniae in 2 patient’s 33.3%, S. epidermidis with E. coli in 2 patient’s 33.3%, S. epidermidis with P. aeruginosa in 1 patient 16.6%, and S. aureus with K. pneumoniae in 1 patient 16.6%. (NS) oil has antibacterial activity against S. aureus and S. epidermidis. Almond oil, silver sulfadiazine, and hydrogen peroxide 3% were the only showed antibacterial activity. Conclusion: Tissue specimen is a good method for bacterial isolation in DFU. (NS) oil, almond oil, and some compounds have antibacterial properties.

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    Author(s) Name:

    Enas A. Bady1 *, Azhar Y. Ibrahim1 , Abdul Hussein K. Marzoq2

    Affiliation(s) Name:

    1 Department of Clinical Laboratories Sciences, College of Pharmacy, University of Basrah, Iraq,

    2 Department of Clinical Laboratories Sciences, Al-Fayhaa Hospital, Basrah, Iraq

    *Corresponding author: Enas A. Bady, Department of Clinical Laboratories Sciences, College of Pharmacy, University of Basrah, Basrah, Iraq.

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    Author:

    Enas A. Bady1 *, Azhar Y. Ibrahim1 , Abdul Hussein K. Marzoq2

    Title:The effect of Nigella sativa and other plants on bacteria isolated from diabetic foot ulcers
    Journal:Drug Invention Today
    Vol(issue):11 (October )
    Year:2019
    Page No: (2434-2439)
  • Experimental Methods Keywords

    Methodology:Bacteria, Diabetic foot infections
    Research Materials: Nigella sativa and other plants

Keywords

Bacteria Diabetic foot infections Essential oils Tissue specimen

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