Journal: Drug Invention Today

Article Id: JPRS-P col-00004134
Title: The evaluation of effectiveness of pharmaceutical correction of the physiological stomach function with the use of information technologies
Category: Pharmaceutics
Section: Research Article
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    Aim: The paper describes the potential use of the drug “trimebutine” in children. It presents the results of the research of its effectiveness in teenagers at the moment of exacerbation of chronic gastritis with regard to an accelerated motor- evacuation function of the stomach. Materials and Methods: In the course of the study, such methods as a clinic anamnestic survey, an observational supersonic scanning of abdominal space with examining the gallbladder function, and a supersonic scanning of stomach with examining its motor-emptying function are used. The study has been conducted regarding the voluntary informed consent of the patients. The design of the study is aligned with accordance to the Helsinki Declaration of the World Medical Association and has been approved on the meeting of the local ethics committee. Results: The results presented in the current study, verify that trimebutine (“trimedate”) is a regulator of a motor function of gastrointestinal tract and possesses a significant pain-alleviating effect, caused by its unspecific effect on all the types of opiate receptors. Conclusion: Nevertheless, it should be noted that the effect of the discussed drug on the children of other age groups as well as the children with a normal or slower emptying function of stomach needs further researching.

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    Author(s) Name:

    Nina G. Terenteva1 , Ekaterina V. Terenteva2 *, Elena V. Suvorova1 , Yuliya V. Somova1 , Oksana Y. U. Ilyina1 , Alexei Wong3

    Affiliation(s) Name:

    1 Department of Industrial Ecology and Life Safety, Nosov Magnitogorsk State Technical University, Magnitogorsk, Lenin Street, 38, Russia,

    2 National Research South Ural State University, Chelyabinsk, Lenin Prospekt, 76, Russia,

    3 Department of Health and Human Performance, Marymount University, 2807 North Glebe Road, Arlington, USA

    *Corresponding author: Ekaterina V. Terenteva, National Research South Ural State University, Chelyabinsk, Lenin Prospekt, 76, Russia

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    Author:

    Nina G. Terenteva1 , Ekaterina V. Terenteva2 *, Elena V. Suvorova1 , Yuliya V. Somova1 , Oksana Y. U. Ilyina1 , Alexei Wong3

    Title:The evaluation of effectiveness of pharmaceutical correction of the physiological stomach function with the use of information technologies
    Journal:Drug Invention Today
    Vol(issue):11 (October )
    Year:2019
    Page No: (2458-2461)
  • Experimental Methods Keywords

    Methodology:Physiological stomach function , information technologies
    Research Materials:Teenagers

Keywords

Children Stomach diseases Trimebutine

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