Journal: Journal of Pharmacy Research
Title: Synthesis of N-acyl heterocycles using conventional and microwave-assisted dry media technique
Category: Pharmaceutical Chemistry
Section: Research Article
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Abstract
A rapid and efficient synthesis of acyl derivatives of N-heterocycles has been performed via the Schotten Bauman reaction. Reactants impregnated individually, on basic alumina, and exposed to microwave irradiation in the presence of base as a catalyst, wherein not only the reaction times have been brought down from hours to minutes in comparison to conventional heating but also the yields of products were improved. New N-acyl heterocycles have been prepared for the first time by microwave-assisted dry media technique and conventional method.
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About the authors and Affiliations
Author(s) Name: Vasanti Suvarna* 1
Affiliation(s) Name: 1S.V.K.M’S, Dr. Bhanuben Nanavati College of Pharmacy,Mithibhai College Campus, V.M.Road. Vile Parle- (W), Mumbai - 400 056.
For correspondence:Vasanti Suvarna,S.V.K.M’S, Dr. Bhanuben Nanavati College of Pharmacy,Mithibhai College Campus, V.M.Road. Vile Parle- (W), Mumbai - 400 056.
E-mail: vasantimmsuvarna@yahoo.com
Received on: 07-05-2008; Accepted on :22-08-2008-
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Author: Vasanti Suvarna* 1
Title: Synthesis of N-acyl heterocycles using conventional and microwave-assisted dry media technique Journal: Journal of Pharmacy Research Vol(issue): 1 (Oct-December 2008) Year: 2008 Page No: (240-244) -
Experimental Methods Keywords
Methodology: Schotten Bauman reaction,microwave Research Materials: N- Acyl-heterocycles
Keywords
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