Journal: Drug Invention Today

Article Id: JPRS-P col-00004214
Title: Cytomorphometric indicators of the gingiva epitheliocytes of patients with ischemic heart disease on the background of taking acetylsalicylic acid
Category: Pharmaceutics
Section: Research Article
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    Aim: The aim is to study the cytological and morphometric characteristics of gingiva epitheliocytes in patients with IHD who are constantly taking ASA drugs. Materials and Methods: To determine the dental status, 92 patients aged 40–60 years who are on outpatient treatment of IHD were examined. All examined patients had received standard therapy for 1–3 years. Result and Discussion: For the purpose of conducting cytomorphometric studies, 56 patients were selected, who constituted the main group. For the purpose of conducting cytomorphometric studies, 56 patients who constituted the main group were selected. The control group included 20 somatically healthy individuals, representative by sex and age. Exclusion criteria from the study were the presence of acute inflammatory processes in the oral cavity, other concomitant somatic pathologies (endocrine diseases and pathology of the gastrointestinal tract), women in the post-menopausal period, as well as patients with tobacco addiction. Conclusion: Due to the high prevalence of periodontal disease in patients with cardiovascular disorders, an in-depth scientific study was conducted and the results of cytomorphometric indicators of the gingiva epitheliocytes of patients with ischemic heart disease, constantly taking acetylsalicylic acid drugs, were presented. The data presented by the authors of the study indicate reliable differences in these indicators in patients of the main group in comparison with the group of somatically healthy patients. The results of the study may be the basis for further in-depth study for early diagnosis of periodontal disease in this category of patients. The results of the study can be the basis for further in-depth study for the purpose of early diagnosis of periodontal disease in this category of patients.

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    Author(s) Name:

    Dmitry V. Emelyanov, Alexander A. Ponomarev*, Valery K. Leontiev, Sergey N. Gontarev, Irina V. Voytyatskaya

    Affiliation(s) Name:

    Department of Therapeutic Dentistry, National Medical Research University, Belgorod State University, 308000, Belgorod, Pobeda Street, 85, Russia

    *Corresponding author: Alexander A. Ponomarev, National Medical Research University, Belgorod State University, 308000, Belgorod, Pobeda Street, 85, Russia.

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    Author:

    Dmitry V. Emelyanov, Alexander A. Ponomarev*, Valery K. Leontiev, Sergey N. Gontarev, Irina V. Voytyatskaya

    Title:Cytomorphometric indicators of the gingiva epitheliocytes of patients with ischemic heart disease on the background of taking acetylsalicylic acid
    Journal:Drug Invention Today
    Vol(issue):12 (October)
    Year:2019
    Page No: (2233-2235)
  • Experimental Methods Keywords

    Methodology:Gingival epithelium, Morphometric analysis, Myocardial infarction
    Research Materials:Acetylsalicylic acid

Keywords

Acetylsalicylic acid Gingival epithelium Morphometric analysis Myocardial infarction

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