Journal: Drug Invention Today
Title: Genetics as a risk factor in periodontitis – A review
Category: Pharmaceutics
Section: Review Article
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Abstract
Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge. Many studies have provided a valuable contribution to understanding the genetic basis of periodontal disease, but the specific candidate genes of susceptibility are still unknown. In fact, genome-wide studies and screening of single-nucleotide polymorphisms have yielded new genetic information without a definitive solution for the management of periodontal disease. In this manuscript, we provide an overview of the most relevant literature, presenting the main concepts and insights of the strategies that have been emerging to better diagnose and treat periodontal disease based on biomarker analysis and host modulation.
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About the authors and Affiliations
Author(s) Name: Sharmila Balachandran, Dhanraj Ganapathy*, Visalakshi Ramanathan
Affiliation(s) Name: Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
*Corresponding author: Dhanraj Ganapathy, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
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Author: Sharmila Balachandran, Dhanraj Ganapathy*, Visalakshi Ramanathan
Title: Genetics as a risk factor in periodontitis – A review Journal: Drug Invention Today Vol(issue): 12 (October) Year: 2019 Page No: (2270-2273) -
Experimental Methods Keywords
Methodology: Diagnosis, Genetic predisposition to disease, Periodontitis, Risk factors Research Materials: periodontitis
Keywords
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