Journal: Drug Invention Today
Title: Acute toxicity of ethanolic extract of Turkcap (Malvaviscus arboreus Cav.) leaves
Category: Pharmacology
Section: Research Article
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Abstract
Background: Turkcap (Malvaviscus arboreus Cav., Malvaceae) leaves, empirically, are used as a hair growth stimulant in the Salawu area, Tasikmalaya district, Indonesia. Ethanolic extract of Turkcap leaves contains polyphenols, essential oils, terpenoids, saponins, and sapogenin. Aim: The purpose of this study was to determine the acute toxicity of Turkcap leaves ethanolic extracts on Swiss Webster mice. Materials and Methods: Mice were given Turkcap leaves ethanolic extract at a dose of 500, 2500, 5000, 10000, and 15000 mg/kg body weight mice. Results: The safety level of Turkcap leaves ethanolic extract was 6th category, i.e., relatively harmless, based on the classification of the OECD Guidelines for the Testing of Chemicals. Conclusion: Turkcap leaves were safe.
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About the authors and Affiliations
Author(s) Name: Nyi Mekar Saptarini*, Resmi Mustarichie
Affiliation(s) Name: Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl Raya Bandung Sumedang Km 21, West Java, Indonesia
*Corresponding author: Nyi Mekar Saptarini, Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl Raya Bandung Sumedang Km 21, West Java 45363, Indonesia.
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Author: Nyi Mekar Saptarini*, Resmi Mustarichie
Title: Acute toxicity of ethanolic extract of Turkcap (Malvaviscus arboreus Cav.) leaves Journal: Drug Invention Today Vol(issue): 11 (November ) Year: 2019 Page No: (2966-2968) -
Experimental Methods Keywords
Methodology: Acute toxicity study Research Materials: Turkcap (Malvaviscus arboreus Cav.) leaves
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