Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004392
Title: Acute toxicity of ethanolic extract of Turkcap (Malvaviscus arboreus Cav.) leaves
Category: Pharmacology
Section: Research Article
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    Background: Turkcap (Malvaviscus arboreus Cav., Malvaceae) leaves, empirically, are used as a hair growth stimulant in the Salawu area, Tasikmalaya district, Indonesia. Ethanolic extract of Turkcap leaves contains polyphenols, essential oils, terpenoids, saponins, and sapogenin. Aim: The purpose of this study was to determine the acute toxicity of Turkcap leaves ethanolic extracts on Swiss Webster mice. Materials and Methods: Mice were given Turkcap leaves ethanolic extract at a dose of 500, 2500, 5000, 10000, and 15000 mg/kg body weight mice. Results: The safety level of Turkcap leaves ethanolic extract was 6th category, i.e., relatively harmless, based on the classification of the OECD Guidelines for the Testing of Chemicals. Conclusion: Turkcap leaves were safe.

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    Author(s) Name:

    Nyi Mekar Saptarini*, Resmi Mustarichie

    Affiliation(s) Name:

    Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl Raya Bandung Sumedang Km 21, West Java, Indonesia

    *Corresponding author: Nyi Mekar Saptarini, Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl Raya Bandung Sumedang Km 21, West Java 45363, Indonesia.

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    Author:

    Nyi Mekar Saptarini*, Resmi Mustarichie

    Title:Acute toxicity of ethanolic extract of Turkcap (Malvaviscus arboreus Cav.) leaves
    Journal:Drug Invention Today
    Vol(issue):11 (November )
    Year:2019
    Page No: (2966-2968)
  • Experimental Methods Keywords

    Methodology:Acute toxicity study
    Research Materials:Turkcap (Malvaviscus arboreus Cav.) leaves

Keywords

Acute toxicity Ethanolic extract Non-toxic Safe Turkcap leaves

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