Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004427
Title: Effect of Vitamin D supplement in improving pain, sleep, and quality of life on patients with chronic low back pain
Category: Pharmacology
Section: Research Article
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    Objectives: The objectives of the study were to assess the intensity of pain in patients before Vitamin D supplements and post supplements, and to identify a therapy that reduces pain and improves the quality of life (QOL) of patients with minimal or no adverse effects. Materials and Methods: The patients enrolled in the study were assessed for their pain, sleep, and QOL using widely accepted testing categories such as visual analogue scale and numerical rating scale for pain, pittsburgh sleep quality index (PSQI) for sleep, and World Health Organization Quality of Life Instruments for QOL. The testing for improvement in pain, sleep, and QOL was assessed at baseline (before Vitamin D supplements) and monitored post Vitamin D supplements. The testing was assessed 2 times–at baseline and after 8 weeks. The improvement in pain, sleep, and QOL was determined by comparing the scores obtained by the individual from the two intervals. Results: The study included 40 patients in which all were cases diagnosed with chronic low back pain (CLBP). Among 40 patients, with ages 36–45 years are at maximum affected by CLBP. Among the 40 patients, 24 patients (60%) are male and 16 patients (40%) are females. From the parameters, 90% of the patients were free from social habits. When LBP, QOL, and sleep quality of the patients were studied using questionnaires, before and after the administration of Vitamin D supplementation. When QOL was compared, after treatment phase showed positive results. QOL was statistically significant between the phase (P < 0.006). Conclusion: Vitamin D supplementation has shown improvement in LBP by exerting immunological influences, thus decrement in pain is noted. The main mechanism through which Vitamin D supplementation reduces pain is its influences in the pain pathway by decreasing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Vitamin D supplementation thereby decreasing the pain increases the sleep and QOL of the patients with LBP.

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    Author:
    Title:Effect of Vitamin D supplement in improving pain, sleep, and quality of life on patients with chronic low back pain
    Journal:Drug Invention Today
    Vol(issue):12 (November )
    Year:2019
    Page No: (2508-2510)
  • Experimental Methods Keywords

    Methodology:improving pain, sleep, and quality of life on patients with chronic low back pain
    Research Materials:Vitamin D

Keywords

Pain Quality of life Sleep Vitamin D

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